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Vestronidase alfa

Vestronidase alfa was FDA-approved on November 17th, 2017 under the trade name Mepsevii as an intravenous infusion for the treatment of pediatric and adult patients. … The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as human beta-glucuronidase (GUS) [FDA Label].

Brensocatib

[A274348,A274343] It reduces exacerbations and slows lung function decline, offering a targeted approach to managing NCFB. … [A274348] Brensocatib was approved by the US FDA on August 12, 2025, for use in adults and pediatric patients with NCFB.[L53808,L53813]

VB10.16

It is composed of three parts, one encodes the E6/E7 fusion protein of human papillomavirus (HPV) type 16 (HPV16), a dimerization entity, and the part encoding a protein that specifically binds to antigen-presenting

Oportuzumab monatox

VB4-845 is a fusion protein containing humanized scFv specific for the epithelial cell adhesion molecule, Ep-CAM, a tumor cell-associated target highly expressed on carcinoma cells of epithelial origin

Nelotanserin

It is a highly selective antagonist at the 5-HT2A serotonin receptor. It increases non-REM sleep, the most restorative phase of the sleep cycle, without sacrificing REM or dream sleep. … Nelotanserin has been used in trials studying the treatment of Lewy Body Dementia, Visual Hallucinations, Dementia With Lewy Bodies, and REM Sleep Behavior Disorder.

BNC105

Cyanamide

A cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide.

Maduramicin

It is a naturally occurring compound which was first isolated from the actinomycete, Actinomadura rubra. … Maduramicin is an antiprotozoal agent used in veterinary medicine as prophylaxis against coccidiosis.

Virginiamycin M1

It is produced by Streptomyces graminofaciens and other bacteria.

Telaprevir

Subtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. … Telaprevir was available as a fixed dose product (tradename Incivek) used for the treatment of chronic Hepatitis C.