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ACR-16
go.drugbank.com/drugs/DB05371InvestigationalACR16 has been successfully investigated in a Phase II multi-centre, randomised and placebo-controlled trial in patients with Huntington’s disease as well as in three Phase Ib studies within Huntington … ACR-16 is also being studied in other psychiatric and neurologic diseases.
Vesnarinone
go.drugbank.com/drugs/DB12082InvestigationalVesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.
Categories: Compounds used in a research, industrial, or household settingProcainamide
go.drugbank.com/drugs/DB01035ApprovedA derivative of procaine with less CNS action.
Synonyms: p-Amino-N-(2-diethylaminoethyl)benzamideIbuproxam
go.drugbank.com/drugs/DB08955ApprovedWithdrawnIbuproxam is a non steroidal anti-inflammatory drug (NSAID).
Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDSCytisine
go.drugbank.com/drugs/DB09028InvestigationalAlso known as baptitoxine or sophorine, cytisine has been used as a smoking cessation treatment since 1964, and is relatively unknown in regions outside of central and Eastern Europe. … Recent Phase III clinical trials using Tabex (a brand of Cytisine marketed by Sopharma AD) have shown similar efficacy to varenicline, but at a fraction of the cost.
Synonyms: (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido[1,2a][1,5]diazocin-8-oneCategories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceEniluracil
go.drugbank.com/drugs/DB03516InvestigationalEniluracil, which was previously under development by GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5-fluorouracil (5-FU), one of the world’ … s most widely-used oncology agents. 5-FU is widely used in the U.S. and is often first or second line therapy for a variety of cancers including colorectal, breast, gastric, head and neck, ovarian and
NADH
go.drugbank.com/drugs/DB00157ApprovedNutraceuticalNADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH, a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. … It forms NADP with the addition of a phosphate group to the 2' position of the adenosyl nucleotide through an ester linkage. (Dorland, 27th ed)
Hexamidine
go.drugbank.com/drugs/DB03808ApprovedInvestigationalMixtures: Imazol duo 10 mg/g + 2,5 mg/g CremeBenzododecinium
go.drugbank.com/drugs/DB13282InvestigationalBenzododecinium is used as an antiseptic/disinfectant compound. It has been marketed as a tincture for antiseptic product for wounds in the Czech Republic.
Categories: Compounds used in a research, industrial, or household settingISS-1018
go.drugbank.com/drugs/DB05463InvestigationalIt is also being investigated in combination with rituximab for treatment of b-cell or non-hodgkin's lymphoma. … ISS 1018 signals through Toll-like receptor 9 (TLR9) to induce the production of immunoglobulin by B cells and interferon (IFN) -alpha, IFN-beta, interleukin-12 (IL-12), and tumor necrosis factor - alpha