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Displaying results 4231 - 4240 of 10000 in total
  1. Drug

    Pozelimab

    go.drugbank.com/drugs/DB15218
    ApprovedInvestigational

    autoimmune hemolysis that are often observed in CHAPLE disease. … CD55-deficient protein-losing enteropathy (PLE), or CHAPLE disease, is an ultra-rare hereditary disease, with fewer than 100 patients diagnosed worldwide or fewer than 10 patients in the US.

  2. Drug

    Pucotenlimab

    go.drugbank.com/drugs/DB17552
    ApprovedInvestigational

    It received its first global approval in China in July 2022 for the treatment of solid tumours.[A257296] It is being investigated in other cancers.

  3. Drug

    INGN 225

    go.drugbank.com/drugs/DB05325
    Investigational

    INGN 225 is currently in Phase 1/2 trials in patients with small cell lung cancer and breast cancer. … INGN 225 is a therapeutic consisting of a cancer patient's own immune cells treated with an adenovector carrying the human p53 gene, Ad-p53.

  4. Drug

    TAS-106

    go.drugbank.com/drugs/DB06656
    Investigational

    TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours [A31693].

  5. Drug

    Melperone

    go.drugbank.com/drugs/DB09224
    Investigational

    It has been well established in the treatment of confusion, anxiety, restlessness (particularly in the elderly) and schizophrenia as It is known to be well-tolerated with an excellent safety profile. … Melperone has been used for a span of greater than 30 years in the European Union [L1316].

  6. Drug

    ORG-34517

    go.drugbank.com/drugs/DB05423
    Investigational

    It has potential to treat a number of diseases such as Cushing’s disease, hypertension, diabetes, glaucoma etc, in which the activity of metabolites corticosterone and cortisol is high.

  7. Drug

    Tolu balsam

    go.drugbank.com/drugs/DB11223
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Trandolaprilat

    go.drugbank.com/drugs/DB14209
    Experimental

    The active metabolite of the prodrug Trandolapril.

    Categories: Agents Acting on the Renin-Angiotensin System
  9. Drug

    Thenoyltrifluoroacetone

    go.drugbank.com/drugs/DB04795
    Experimental

    Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    NXN-188

    go.drugbank.com/drugs/DB06096
    Investigational

    NXN-188 is a first-in-class, dual-action small molecule incorporating both neuronal nitric oxide synthase (nNOS) inhibition and 5-HT agonism that is being developed for the treatment of acute migraine.