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Nabiximols
go.drugbank.com/drugs/DB14011InvestigationalIn contrast to THC's weak agonist activity, CBD has been shown to act as a negative allosteric modulator of the cannabinoid CB1 receptor, the most abundant G-Protein Coupled Receptor (GPCR) in the body … Nabiximols (tradename Sativex®) is a whole plant extract from the Cannabis species _Cannabis sativa L._ that has been purified into the active components CBD (cannabidiol) and THC (delta-9-tetrahydrocannabinol
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsArimoclomol
go.drugbank.com/drugs/DB05025Approved[L51384] Arimoclomol was approved by the FDA on September 20, 2024, making it the first treatment for Niemann-Pick disease, type C (NPC). … Arimoclomol is a hydroxylamine derivative [A264414] and a heat-shock protein-70 (HSP70) co-inducer.
Synonyms: 3-PYRIDINECARBOXIMIDOYL CHLORIDE, N-((2R)-2-HYDROXY-3-(1-PIPERIDINYL)PROPOXY), 1-OXIDE, N-[(2R)-2-Hydroxy-3-(1-piperidyl)propoxy]pyridine-3-carboximidoyl chloride, 1-oxideCategories: MATE 1 Substrates, MATE 2 SubstratesNitrazepam
go.drugbank.com/drugs/DB01595ApprovedA benzodiazepine derivative used as an anticonvulsant and hypnotic.
Synonyms: 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one, 2,3-dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-oneCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingRentiapril
go.drugbank.com/drugs/DB20567ExperimentalRentiapril is a small molecule drug. The usage of the INN stem '-pril' in the name indicates that Rentiapril is a angiotensin-converting enzyme inhibitor. … Rentiapril has a monoisotopic molecular weight of 313.04 Da.
Categories: Agents Acting on the Renin-Angiotensin SystemDocosanol
go.drugbank.com/drugs/DB00632ApprovedDocosanol inhibits fusion between the plasma membrane and the herpes simplex virus (HSV) envelope, thereby preventing viral entry into cells and subsequent viral replication. … Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters).
Synonyms: 1-Docosanol, Docosan-1-olProducts: Erazaban 100 mg/g CremeFinafloxacin
go.drugbank.com/drugs/DB09047ApprovedWithdrawnFinafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014. … Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus.
Synonyms: 8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acidCategories: 4-Quinolones, Heterocyclic Compounds, 2-RingIoflupane I-123
go.drugbank.com/drugs/DB08824ApprovedInvestigationalIoflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Synonyms: Ioflupane I 123, Ioflupane I-123Products: Ioflupane I 123, DATSCAN 74 MBQ/ML ENJEKSİYONLUK ÇÖZELTİ, 5 MLFlumequine
go.drugbank.com/drugs/DB08972ApprovedWithdrawnFlumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingEtamivan
go.drugbank.com/drugs/DB08989ApprovedWithdrawnEtamivan (INN) or ethamivan (USAN) is marketed under the name Analepticon. Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States.
Viper antivenom
go.drugbank.com/drugs/DB14114ApprovedInvestigationalANAVIP, an equine-derived antivenom made with venom from _Bothrops asper_ and _Crotalus durissus_, was first approved by the FDA on October 1, 2015, for the management of North American rattlesnake envenomation
Synonyms: Crotalidae immune F(ab')2 (equine), Antivenin crotaline (pit-viper) equine immune F(ab)2)