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PX-478
go.drugbank.com/drugs/DB06082InvestigationalPX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical trial in patients with advanced metastatic cancer and lymphoma. … PX-478 was effective in models of both non-small cell lung cancer and small cell lung cancer that express HIF-1 alpha.
Methyl 2,5-dihydroxycinnamate
go.drugbank.com/drugs/DB16769ExperimentalCategories: Compounds used in a research, industrial, or household settingErgothioneine
go.drugbank.com/drugs/DB17614InvestigationalCategories: Compounds used in a research, industrial, or household settingCimicoxib
go.drugbank.com/drugs/DB05095InvestigationalIf approved, Cimicoxib would be the first drug in decades to treat depression by a new mechanism of action.
Troxacitabine
go.drugbank.com/drugs/DB04961InvestigationalThere has been growing interest in its development for the treatment of patients with refractory lymphoproliferative conditions.
CY301
go.drugbank.com/drugs/DB06382ExperimentalCY301 (Simplivir) is an investigational gene silencing compound developed by CytoGenix for the treatment of HSV.
G17DT Immunogen
go.drugbank.com/drugs/DB04914InvestigationalIt is also in a phase II/III trial for advanced stomach cancer in combination with 5-fluorouracil and cisplatin and in a late phase II trial for advanced colorectal cancer in combination with irinotecan … It is in phase III trials for advanced pancreatic cancer as a monotherapy and in combination with gemcitabine.
Synonyms: G17DT (AN ANTIGASTRIN IMMUNOGEN)Meclofenamic acid
go.drugbank.com/drugs/DB00939ApprovedInvestigationalVet approvedA non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Synonyms: N-(2,6-dichloro-m-tolyl)anthranilic acid, N-(2,6-dichloro-3-methylphenyl)anthranilic acidGPI-1485
go.drugbank.com/drugs/DB05814InvestigationalGPI 1485 is being studied in phase 2 clinical trials for the treatment of Parkinson's disease and post-prostatectomy erectile dysfunction and in pre-clinical development for HIV related dementia and neuropathy … In preclinical experiments, neuroimmunophilin ligands have been shown to repair and regenerate damaged nerves without affecting normal, healthy nerves.