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Fenspiride
go.drugbank.com/drugs/DB08979InvestigationalIt is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis
VB10.16
go.drugbank.com/drugs/DB17512InvestigationalIt is composed of three parts, one encodes the E6/E7 fusion protein of human papillomavirus (HPV) type 16 (HPV16), a dimerization entity, and the part encoding a protein that specifically binds to antigen-presenting
Angiotensin II
go.drugbank.com/drugs/DB11842ApprovedInvestigationalThe novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin II to help maintain body blood pressure.
Plerixafor
go.drugbank.com/drugs/DB06809ApprovedInvestigational[A7117,L45678] It is used to stimulate the release of stem cells from the bone marrow into the blood in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma to stimulate their immune system.
Odronextamab
go.drugbank.com/drugs/DB16684ApprovedInvestigational[A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can lead to the development
αAβ–Gas6
go.drugbank.com/drugs/DB17069Experimental[A253213] This experimental drug gained attention because it was associated with fewer inflammatory side effects than the previously-approved Aβ antibody-based immunotherapy, [aducanumab].[L43428] … It is made of a single chain variable fragment (scFv) of an Amyloid β (Aβ)-targeting monoclonal antibody fused with a truncated receptor binding domain of growth arrest-specific 6 (Gas6), which is a ligand
Ty800
go.drugbank.com/drugs/DB04989InvestigationalIt is being developed by AVANT Immunotherapeutics, Inc.
EPC2407
go.drugbank.com/drugs/DB05189InvestigationalIt is intended for the treatment of advanced cancer patients with solid tumors that are well vascularized.
Polyvalent antigen-KLH conjugate vaccine
go.drugbank.com/drugs/DB17565InvestigationalIt is under investigation in clinical trial NCT01223235 (Polyvalent Vaccine-klh Conjugate + Opt-821 Given in Combination With Bevacizumab).
AC-003
go.drugbank.com/drugs/DB22691Investigational[L53458] It is being investigated for the treatment of acute graft-versus-host disease (GVHD) and idiopathic pulmonary fibrosis (IPF).[L53458]