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Displaying results 4301 - 4310 of 10000 in total
  1. Drug

    Pipamperone

    go.drugbank.com/drugs/DB09286
    Investigational

    It was developed by Janssen Pharmaceutica in 1961 and started its first round of clinical trials in 1963 [L1514, L1518]. … In an effort to improve [haloperidol]'s pharmacological effects, Janssen discovered that pipamperone, an agent whose pharmacological profile was distinct from haloperidol and all other known antipsychotic

  2. Drug

    TAS-106

    go.drugbank.com/drugs/DB06656
    Investigational

    TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours [A31693].

  3. Drug

    Rilapladib

    go.drugbank.com/drugs/DB05119
    Investigational

    Lp-PLA2 is an enzyme associated with the formation of atherosclerotic plaques.

  4. Drug

    ISIS 113715

    go.drugbank.com/drugs/DB05506
    Investigational

    In early trials, ISIS 113715 induced statistically significant improvements in multiple measures of glucose control along with statistically significant reductions in LDL-cholesterol.

  5. Drug

    APD668

    go.drugbank.com/drugs/DB05166
    Experimental

    APD668 is a novel, highly potent and orally active glucose-dependent insulinotropic receptor (GDIR) agonist intended to more efficiently stimulate insulin release by beta cells in response to elevated

  6. Drug

    Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen

    go.drugbank.com/drugs/DB10801
    ApprovedInvestigational

    diphtheriae* grown in another culture. … Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria

  7. Drug

    4-dimethylaminophenol

    go.drugbank.com/drugs/DB13549
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Gleptoferron

    go.drugbank.com/drugs/DB11417
    ExperimentalVet approved

    Colloid solution of ferric hydroxide, dextran & glucoheptonic acid.

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Halothane

    go.drugbank.com/drugs/DB01159
    ApprovedVet approvedWithdrawn

    A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce suffi...

  10. Drug

    Omburtamab

    go.drugbank.com/drugs/DB15635
    Investigational

    [A242487, A242492] Omburtamab, formerly the murine anti-B7-H3 antibody 8H9, and its humanized forms are currently under clinical development for use in various cancers. … [A191829] Omburtamab is under investigation in clinical trial NCT03275402 (131i-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/leptomeningeal Metastases).