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Mepiprazole
go.drugbank.com/drugs/DB09197ExperimentalIt acts as a 5-HT2A and α1-adrenergic receptor antagonist, and has also been shown to inhibit the reuptake and induce the release of serotonin, dopamine, and norepinephrine to varying extents. … It is a pyrazolyl-alkyl-piperazine derivative. Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons [A7816].
APD668
go.drugbank.com/drugs/DB05166ExperimentalAPD668 is a novel, highly potent and orally active glucose-dependent insulinotropic receptor (GDIR) agonist intended to more efficiently stimulate insulin release by beta cells in response to elevated blood glucose levels, and to also av...
Cardarine
go.drugbank.com/drugs/DB05416InvestigationalCardarine has been investigated for the treatment of Obesity, Lipid Disorders, and Cardiovascular Disease.
Methdilazine
go.drugbank.com/drugs/DB00902ApprovedIt is used in the treatment of various dermatoses to relieve pruritus.
Atipamezole
go.drugbank.com/drugs/DB11481InvestigationalVet approvedIt has also been undergone research as a potential anti-Parkinsonian drug for humans.
DCFBC F-18
go.drugbank.com/drugs/DB14772InvestigationalDCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).
Promestriene
go.drugbank.com/drugs/DB12487InvestigationalIt has been also studied in phase III of the clinical trial in the post-operative patients with hypospadias. … Promestriene (3-propyl ethyl, 17B-methyl estradiol) has been used in trials studying the prevention of Hypospadias. It is a synthetic estrogen analog, which is used in topical estrogen therapy.
Guanoxan
go.drugbank.com/drugs/DB13211ApprovedGuanoxan was approved in the UK but was withdrawn from the market due to hepatotoxicity.