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Rocakinogene sifuplasmid
go.drugbank.com/drugs/DB16316InvestigationalRocakinogene sifuplasmid is under investigation in clinical trial NCT03491683 (INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-diagnosed Glioblastoma
ASP-8731
go.drugbank.com/drugs/DB17696InvestigationalDeveloped by Mitobridge, it is being investigated for the treatment of sickle cell disease.[L46093]
BEA-17
go.drugbank.com/drugs/DB18574Experimental[L48330] It is under investigation for the treatment of glioblastoma.
Tandamine
go.drugbank.com/drugs/DB09192ExperimentalTandamine is an analog of pirandamine and it acts as a selective serotonin reuptake inhibitor (SSRI).
Arsanilic acid
go.drugbank.com/drugs/DB03006ExperimentalVet approvedIt causes blindness and is ototoxic and nephrotoxic in animals. [PubChem]
KC706
go.drugbank.com/drugs/DB05157InvestigationalKC706 is a novel anti-inflammatory drug that works by inhibiting the activity of p38 MAP kinase. KC706 holds potential to treat inflammatory conditions such as rheumatoid arthritis, psoriasis, inflammatory bowel disease and cardiovascula...
Saredutant
go.drugbank.com/drugs/DB06660InvestigationalSaredutant (SR 48968) is a neurokinin-2 antagonist drug being developed as an antidepressant and anxiolytic by Sanofi-Aventis.
Palovarotene
go.drugbank.com/drugs/DB05467ApprovedIt first garnered interest as a potential treatment for emphysema but was eventually recognized as a potential novel therapy for patients with FOP. … [L39990,L40020] It has been granted rare pediatric disease and breakthrough therapy designations from the US FDA, although a previously submitted NDA was withdrawn in August 2021 pending the resubmission
Dirlotapide
go.drugbank.com/drugs/DB11399InvestigationalVet approvedIt is marketed by Pfizer and Zoetis under the brand name, _Slentrol_, and is not intended for human use.
MB-07803
go.drugbank.com/drugs/DB05053InvestigationalIt is designed to block the metabolic pathway in the liver that is responsible for producing glucose.