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Beractant
go.drugbank.com/drugs/DB06761ApprovedIn comparison to synthetic forms of surfacant, natural forms such as Beractant have been found to have a reduced incidence of pneumothorax and reduced mortality. … SP-B and SP-C.
Products: SURVANTA ® 4 ML, SURVANTA INTRATRAKEAL SUSPANSIYON, 1 ADETErdosteine
go.drugbank.com/drugs/DB05057ApprovedInvestigationalErdosteine has been shown to be safe and well tolerated in clinical trials. … Erdosteine is a drug that causes a breakdown of mucus, also known as a _mucolytic_ agent.
Categories: Heterocyclic Compounds, 1-RingProducts: DOSTEIN® CAPSULAS, DOSTEIN® SUSPENSIONUmbralisib
go.drugbank.com/drugs/DB14989ApprovedInvestigationalWithdrawnIt was marketed as Ukoniq by TG Therapeutics and has been approved for the treatment of relapsing and refractory marginal cell lymphoma and follicular lymphoma in adults. … with a possible increased risk of death outweighing the benefits.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesNeomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approved[L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. … [A175042,A191529] Neomycin A, or [neamine], is a moiety that conjoins two molecules of neomycin B and C together.
Mixtures: Green Guard Triple Antibiotic, Green Guard Triple AntibioticCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProstaglandin E synthase
go.drugbank.com/bio_entities/BE0011075TargetHumansTerminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inf...
Synonyms: p53-induced gene 12 proteinCCN family member 3
go.drugbank.com/bio_entities/BE0001147TargetHumansAlso plays a role in cutaneous wound healing acting as integrin receptor ligand.
Synonyms: Nephro blastoma-overexpressed gene protein homologIDM-4
go.drugbank.com/drugs/DB05438ExperimentalTrials of this drug have most likely been discontinued by the manufacturer. … IDM-4 is an immuno-designed molecule that completed phase I/II of investigation for the treatment of Leukemia.
Synonyms: IDM-4Erythroxylum catuaba bark
go.drugbank.com/drugs/DB14300Investigational"Catuaba" is a general term for a medicinal infusion created by the bark of plants belonging to the _Erythroxylum_ genus, though this name is also applied to infusions of plants belonging to other genera … [A215262] The infusion is thought to carry stimulant and aphrodisiac effects,[A215262] and catuaba made specifically with _Trichilia catigua_ has been investigated for use in depression.[A215267]
Mericitabine
go.drugbank.com/drugs/DB12045InvestigationalMericitabine has been investigated for the treatment of Hepatitis C, Chronic. Mericitabine is a polymerase inhibitor being developed for the treatment of chronic hepatitis C. … PSI-6130 is a pyrimidine nucleoside analog inhibitor of HCV RNA polymerase, an enzyme that is necessary for hepatitis C viral replication.
Categories: Heterocyclic Compounds, 1-Ring