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Aminorex
go.drugbank.com/drugs/DB01490ExperimentalIllicitAminorex is an amphetamine-like anorectic agent. It may cause pulmonary hypertension.
Oxfenicine
go.drugbank.com/drugs/DB04291ExperimentalOxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Synonyms: L-2-(p-hydroxyphenyl)glycineD-Lysine
go.drugbank.com/drugs/DB03252ExperimentalAn essential amino acid. It is often added to animal feed. [PubChem]
Synonyms: D-Lysin, D-LysineLinaprazan glurate
go.drugbank.com/drugs/DB21534InvestigationalLinaprazan glurate has a monoisotopic molecular weight of 480.24 Da. … Linaprazan glurate is under investigation in clinical trial NCT07037875 (A Study Comparing the Effect and Safety of Linaprazan Glurate to Lansoprazole in Participants With Erosive Esophagitis (EE) Due
Lebrikizumab
go.drugbank.com/drugs/DB11914ApprovedInvestigationalLebrikizumab is a monoclonal antibody that binds to IL-13 with high affinity and slow off-rate. It binds to a different epitope compared tralokinumab. On November 17, 2023, lebrikizumab was approved by the EMA under the brand name EBGLYS...
Avanafil
go.drugbank.com/drugs/DB06237ApprovedAvanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but l...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesCarprofen
go.drugbank.com/drugs/DB00821ApprovedVet approvedWithdrawnCarprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years...
Pilocarpine
go.drugbank.com/drugs/DB01085ApprovedInvestigationalA naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist. Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InhibitorsGlycerol phenylbutyrate
go.drugbank.com/drugs/DB08909ApprovedInvestigationalGlycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP2D6 InhibitorsGamolenic acid
go.drugbank.com/drugs/DB13854ApprovedWithdrawnIt is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6; 6,9,12-octadecatrienoic acid; and cis-6, cis-9, cis-12- octadecatrienoic acid [F27]. … Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds [F27] that is most commonly found in human milk