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Osanetant
go.drugbank.com/drugs/DB04872InvestigationalIn a review of its R&D portfolio, the company announced in August 2005 that it would cease any further development of osanetant. … This follows an earlier decision to discontinue development of eplivanserin for schizophrenia.
EMZ702
go.drugbank.com/drugs/DB05021InvestigationalEMZ702, a non-toxic agent that has strong anti-viral synergy with interferon, is an ideal candidate for combination with current standard hepatitis C treatments. … EMZ702 has an excellent safety profile and the combination of EMZ702 with interferon and ribavirin in surrogate models for hepatitis C has demonstrated a two to three fold increase in anti-viral potency
Erlotinib
go.drugbank.com/drugs/DB00530ApprovedInvestigationalof patients with idiopathic myelofibrosis or essential thrombocythemia. … Recent studies demonstrate that erlotinib is also a potent inhibitor of JAK2V617F, which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and a substantial proportion
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexFerric sulfate
go.drugbank.com/drugs/DB11171ApprovedFerric sulfate has the molecular formula of Fe2SO4, and it is a dark brown or yellow chemical agent with acidic properties. It is produced by the reaction of sulfuric acid and an oxidizing agent. … [A32355, A32356] By the FDA, ferric sulfate is a direct food substance affirmed in the GRAS category (Generally Recognized As Safe).[L2003]
GMK
go.drugbank.com/drugs/DB06661ExperimentalGMK vaccine (a ganglioside conjugate vaccine coupled to keyhole limpet hemocyanin and formulated with the adjuvant QS-21) for the potential treatment of melanoma
Morinamide
go.drugbank.com/drugs/DB13417InvestigationalCategories: Antiinfectives for Systemic Use, Drugs for Treatment of TuberculosisADX-10061
go.drugbank.com/drugs/DB05419ExperimentalADX10061 is a potent, selective antagonist of the dopamine D1 receptor. It is developed by Addex Pharmaceuticals for the treatment of nicotine dependence.
Senicapoc
go.drugbank.com/drugs/DB06280InvestigationalSenicapoc (ICA-17043) is a novel Gardos channel blocker.[A259068] It is being investigated for the treatment of sickle cell disease.
Abciximab
go.drugbank.com/drugs/DB00054ApprovedWithdrawnAbciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3.
Talinolol
go.drugbank.com/drugs/DB11770InvestigationalTalinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.