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Volixibat

If approved for use, it will be the first available agent for the treatment of NASH. … the liver have been implicated in its pathogenesis[A32119].

KW-7158

The therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels which regulate afferent neuron excitability and firing properties in the dorsal root ganglion

BB 21217

BB 21217 is an anti-BCMA CAR T cell therapy that uses the same CAR molecule as [idecabtagene vicleucel] (bb2121), but adds the PI3K inhibitor bb007 during ex vivo culture to enrich the drug product (DP … ) for memory-like T cells.

Barbital

A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. … Barbital is also used in veterinary practice for central nervous system depression. Barbital is a schedule IV controlled drug.

RUS 3108

The drug’s Phase I clinical trials have been initiated in Europe to assess safety of the drug compound in healthy volunteers.

ILY101

ILY101 is designed to allow for lower daily doses and improved patient acceptance and tolerability in comparison to other products in this class of drugs. … ILY101 is being developed for the treatment of hyperphosphatemia in CKD patients on dialysis and works by reducing the systemic absorption of dietary phosphate.

Pentetreotide

Pentetreotide has been used in trials studying the diagnosis of Cushing's syndrome.

Kojic acid

REN-850

REN-850 is an oral drug for multiple sclerosis which is in Phase I of clinical trials.

Peramivir

Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. … Being an influenza virus neuraminidase inhibitor, peramivir works by preventing new viruses from emerging from infected cells.