Barbital

DB01483ExperimentalIllicitSmall molecule

A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice... Barbital is a schedule IV controlled drug.

Mechanism: Pharmacologically active on Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit alpha-2, and Gamma-aminobutyric acid receptor subunit alpha-3
Curator reviewed
Formula / weight: C₈H₁₂N₂O₃ · 184.1925 g/mol (avg)

Resolves to

Compound

UNII5WZ53ENE2PCAS57-44-3ChEMBLCHEMBL444ChEBI31252PubChem2294KEGGC02517

Clinical / RWD

RxNorm1325ATCN05CA04PharmGKBPA448538

Structure

InChIKeyFTOAOBMCPZCFFF-UHFFFAOYSA-NSMILESCCC1(CC)C(=O)NC(=O)NC1=O

Targets

P14867GABRA1P47869GABRA2P34903GABRA3P48169GABRA4P31644GABRA5Q16445GABRA6P43681CHRNA4P36544CHRNA7+2 more

What you can answer from here — as of September 23, 2026

10Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1,437Drug interactionsStructured to mechanism, not free text

1ATC codeIncluding every combination product, plus 23 drug categories

30+ReferencesStructured and connected to the statements they support

Which drugs share a target with Barbital, and which of those have an active Phase 3 trial?

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