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Displaying results 4371 - 4380 of 10000 in total
  1. Drug

    Briquilimab

    go.drugbank.com/drugs/DB18136
    Investigational

    Briquilimab is a humanized aglycosylated IgG1 kappa monoclonal antibody targeting CD117 (cKit).

    Synonyms: IMMUNOGLOBULIN G1 (297-GLUTAMINE), ANTI-(HUMAN C-KIT RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .KAPPA.-CHAIN, DIMER
  2. Drug

    Ulenistamab

    go.drugbank.com/drugs/DB18291
    Investigational

    Synonyms: Immunoglobulin g1, anti-(human pancreatic adenocarcinoma up-regulated factor) (human-mus musculus monoclonal pbp1510 .gamma.1-chain), disulfide with human-mus musculus monoclonal pbp1510 .kappa.
  3. Drug

    Tozorakimab

    go.drugbank.com/drugs/DB16473
    Investigational

    COPD patients with a history of exacerbations), and NCT06040086 (recruiting; symptomatic COPD with a history of exacerbations). … Tozorakimab (MEDI3506), developed by AstraZeneca, was investigated in multiple clinical trials to evaluate its safety, tolerability, efficacy, and pharmacokinetics across various conditions.

    Synonyms: ) L123>M (121)) CDR-IMGT [8.8.19] (26-33.51-58.97-1, Immunoglobulin G1-lambda2, anti-[Homo sapiens IL33 (interleukin 33, DVS27, NF-HEV, IL1F11)], monoclonal antibody; gamma1 heavy chain (1-456) [VH (Homo sapiens IGHV3-23*01 (93.9%) -(IGHD) -IGHJ4*01 (85.7%Categories: Experimental Unapproved Treatments for COVID-19
  4. Drug

    Pegvorhyaluronidase alfa

    go.drugbank.com/drugs/DB14912
    Investigational

    Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection

    Synonyms: HUMAN HYALURONIDASE PH-20 (HYALURONOGLUCOSAMINIDASE PH-20, SPERM ADHESION MOLECULE 1, EC 3.2.1.35) PRECURSOR-(36-482)-PEPTIDE (MATURE (1-447)-PEPTIDE), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM, ALFA, SUBSTITUTED ON N6 OF AN AVERAGE OF 4 TO
  5. Drug

    Irpagratinib

    go.drugbank.com/drugs/DB18732
    Investigational

    Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4.

    Synonyms: 2-Propenamide, N-[(3S,4S)-3-[[6-(2,6-difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-2H-pyran-4-yl]-, N-[(3S,4S)-3-[[6-(2,6-Difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-2H-pyran-4-yl]-2-propenamide
  6. Drug

    Ergoloid mesylate

    go.drugbank.com/drugs/DB01049
    Approved

    [A32914] The mixture of ergoloid mesylate was first developed by Novartis and FDA approved on November 5, 1953, but this specific formulation is now discontinued. … [A32912] All these components are produced by the fungus _Claviceps purpurea_ and are all derivatives of the tetracyclic compound 6-methylergonovine.

    Mixtures: TOTERJİN DAMLA, 50 CCCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    Apomorphine

    go.drugbank.com/drugs/DB00714
    ApprovedInvestigational

    Apomorphine is a non-ergoline dopamine D2 agonist indicated to treat hypomobility associated with Parkinson's. It was first synthesized in 1845 and first used in Parkinson's disease in 1884. … [A203618] Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.

    Categories: Drugs Used in Erectile Dysfunction, Cytochrome P-450 SubstratesSynonyms: (R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol, (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
  8. Drug

    Hydroxyprogesterone caproate

    go.drugbank.com/drugs/DB06789
    Approved

    FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy … Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate.

    Synonyms: 17alpha-Caproyloxypregn-4-ene-3,20-dione, Caproato de hidroxiprogesteronaMixtures: GRAVIDINONA 2 ML
  9. Drug

    Acetylcysteine

    go.drugbank.com/drugs/DB06151
    ApprovedInvestigational

    [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results. … [A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.[L31488]

    Synonyms: N Acetyl L Cysteine, N-acetyl-L-cysteineMixtures: AMINOPLASMAL-5% E INFUSION, AMINOPLASMAL-10% E INFUSION
  10. Drug

    Methylprednisolone hemisuccinate

    go.drugbank.com/drugs/DB14644
    ApprovedInvestigational

    A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

    Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP3A InducersProducts: A-methapred, SOLU-MEDROL DE 40 MG SOLUCION