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Displaying results 4381 - 4390 of 10000 in total
  1. Drug

    Rogocekib

    go.drugbank.com/drugs/DB21739
    Investigational

    Rogocekib is a small molecule drug. Rogocekib has a monoisotopic molecular weight of 408.15 Da.

  2. Drug

    Amifostine

    go.drugbank.com/drugs/DB01143
    ApprovedInvestigational

    A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Talazoparib

    go.drugbank.com/drugs/DB11760
    ApprovedInvestigational

    Talazoparib is an inhibitor of mammalian polyadenosine 5’-diphosphoribose polymerases (PARPs), enzymes responsible for regulating essential cellular functions, such as DNA transcription and DNA repair.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index
  4. Drug

    Felbamate

    go.drugbank.com/drugs/DB00949
    Approved

    It has a weak inhibitory effect on GABA receptor binding sites. … Felbamate is an anticonvulsant drug used in the treatment of epilepsy. In particular, in the adult patient population, it can be employed to treat partial seizures (with and without generalization).

  5. Drug

    Latanoprostene bunod

    go.drugbank.com/drugs/DB11660
    Approved

    In comparison, both latanoprost and latanoprostene bunod contain a latanoprost acid backbone. … Conversely however, latanoprostene bunod integrates an NO-donating moiety in lieu of the isopropyl ester typically found in latanoprost.

  6. Drug

    NGD-4715

    go.drugbank.com/drugs/DB06027
    Experimental

    NGD-4715 is an investigational compound developed for the treatment of Obesity. NGD-4715 functions as a melanin-concentrating hormone receptor 1 antagonist.

  7. Drug

    Fluorfenidine F-18

    go.drugbank.com/drugs/DB19557
    Experimental

    Fluorfenidine F-18 has a monoisotopic molecular weight of 382.07 Da. … Fluorfenidine F-18 is a small molecule drug. The usage of the INN stem '-nidine' in the name indicates that Fluorfenidine F-18 is a a2 adrenoreceptor agonist.

  8. Drug

    Belimumab

    go.drugbank.com/drugs/DB08879
    ApprovedInvestigational

    Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. … It is produced by recombinant DNA technology in a murine cell (NS0) expression system.

  9. Drug

    Poractant alfa

    go.drugbank.com/drugs/DB09113
    ApprovedInvestigational

    Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. … It is used to treat Respiratory Distress Syndrome (RDS) in premature infants with an endogenous pulmonary surfactant deficiency.

  10. Drug

    Isoxepac

    go.drugbank.com/drugs/DB19733
    Experimental

    Isoxepac has a monoisotopic molecular weight of 268.07 Da. … Isoxepac is a small molecule drug. The usage of the INN stem '-ac' in the name indicates that Isoxepac is a anti-inflammatory agent, ibufenac derivative.