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Displaying results 4381 - 4390 of 7059 in total
  1. Drug

    Tavokinogene telseplasmid

    go.drugbank.com/drugs/DB17301
    Investigational

    Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.

    Synonyms: Dna plasmid encoding interleukin-12 ino-9012, DNA Plasmid Vector encoding IL-12 (pUMVC3-hIL-12-NGVL331)
  2. Drug

    Tirabrutinib

    go.drugbank.com/drugs/DB15227
    Investigational

    Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).

  3. Drug

    EA-2353

    go.drugbank.com/drugs/DB18506
    Investigational

    EA-2353 is a small molecule inhibitor of kinase mediators of the Wnt pathway.

  4. Drug

    Methyl-D9-choline

    go.drugbank.com/drugs/DB12628
    Investigational

    Methyl-D9-choline is under investigation in clinical trial NCT01807910 (ER Stress in NAFLD).

  5. Drug

    Daclizumab

    go.drugbank.com/drugs/DB00111
    ApprovedInvestigationalWithdrawn

    This withdrawal was concurrent to the European Medicines Agency announcement of a recall owing to 12 worldwide reports of serious inflammatory brain disorders associated with the use of Zinbryta (daclizumab … Daclizumab is a composite of human (90%) and murine (10%) antibody sequences.

  6. Drug

    APT20TTMG

    go.drugbank.com/drugs/DB32869
    Experimental

    APT20TTMG is a synthetic DNA that modulates U1 small nuclear ribonucleoprotein misassembly.

  7. Drug

    Enzalutamide

    go.drugbank.com/drugs/DB08899
    ApprovedInvestigational

    [L40639] It is a second-generation antiandrogen agent that the FDA approved on August 31, 2012. … [A252667,A252642] Due to a favorable pharmacological profile, a phase 1 study of enzalutamide was initiated in July 2007.

    Products: Enzalutamid 1A Pharma 40 mg - Filmtabletten, Enzalutamid 1A Pharma 80 mg - Filmtabletten
  8. Drug

    IFx-Hu2.0

    go.drugbank.com/drugs/DB18396
    Investigational

    It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.

    Synonyms: Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic, streptococcal Emm55 protein, complexed with in vivo-jetPEI® polymer-based reagent linear
  9. Drug

    AG0302-COVID19

    go.drugbank.com/drugs/DB16435
    Investigational

    Sponsored by Anges, Inc. in Japan, the AG0302-COVID19 is a DNA-based vaccine that recently completed Phase I/II trials (NCT04527081)[A226813, L30548].

  10. Drug

    Lefamulin

    go.drugbank.com/drugs/DB12825
    Approved

    A pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus. … Lefamulin is a pleuromutilin antibiotic used for the treatment of bacterial community-acquired pneumonia.