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Icatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigational[A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema. … relief was observed to be 8 hours compared to 36 hours for the placebo treatment.
Categories: Drugs Used in Hereditary AngioedemaProducts: ICATIBANT EG, Icatibant STADA 30 mg Injektionslösung in einer FertigspritzeLevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigationalIt was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs). … interactions[L8606,L8600,L8615] - these characteristics make it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in
Products: Levetiracetam ER, LEVETIRACETAM EGDiphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalAs histamine receptors exist both peripherally and in the central nervous system, diphenhydramine has been shown to cause sedation due to its competitive antagonism of histamine H1 receptors within the … Diphenhydramine has also been shown to be implicated in a number of neurotransmitter systems that affect behaviour including dopamine, norepinephrine, serotonin, acetylcholine, and opioid [A1539].
Mixtures: BENADRYL-E, BENADRYL EMSynonyms: N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine, 2-(benzhydryloxy)-N,N-dimethylethylaminePropafenone
go.drugbank.com/drugs/DB01182ApprovedInvestigationalAn antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Products: PROPAFENONE EGCalcium acetate
go.drugbank.com/drugs/DB00258ApprovedThe chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Categories: Compounds used in a research, industrial, or household settingProducts: FOSFAT-EX 700 MG FILM TABLET,FILM TABLET, 100 ADETGefitinib
go.drugbank.com/drugs/DB00317ApprovedInvestigationalActing in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa. … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer.
Synonyms: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamineProducts: GEFITINIB EGNintedanib
go.drugbank.com/drugs/DB09079ApprovedInvestigational[L8453,L8459] It was first approved for use in the United States in 2014. … Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC).
Products: NINTEDANIB EGColchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigationalColchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961. … [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602]
Categories: Preparations With No Effect on Uric Acid MetabolismProducts: PMS-colchicine ER, Euro-colchicineArnica montana
go.drugbank.com/drugs/DB14297InvestigationalArnica montana is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: European Arnica WholeCategories: Complex MixturesOxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigationalOxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. … for an extended period.
Mixtures: OSSICODONE E NALOXONE EG, OSSICODONE E NALOXONE EGProducts: OSSICODONE E NALOXONE EG, Xtampza ER