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Displaying results 431 - 440 of 10000 in total
  1. Drug

    Efineptakin alfa

    go.drugbank.com/drugs/DB16395
    Investigational

    Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. … Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response.

    Synonyms: Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody (Rhil-7-Hyfc), Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody (rhIL-7-hyFc).
  2. Drug

    Tefidsogene civaparvovec

    go.drugbank.com/drugs/DB16789
    Investigational

    It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes … Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing.

    Synonyms: EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE (SA), A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS
  3. Drug

    (5R,6S,7S,8S)-5-hydroxymethyl-6,7,8-trihydroxy-tetrazolo[1,5-A]piperidine

    go.drugbank.com/drugs/DB02294
    Experimental

    Synonyms: (5R,6S,7S,8S)-5-hydroxymethyl-6,7,8-trihydroxy-tetrazolo[1,5-A]piperidine
  4. Drug

    6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one

    go.drugbank.com/drugs/DB08036
    Experimental

    Synonyms: 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one
  5. Drug

    4-{[5-(CYCLOHEXYLAMINO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE

    go.drugbank.com/drugs/DB07686
    Experimental

    Synonyms: 4-{[5-(CYCLOHEXYLAMINO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE
  6. Drug

    4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE

    go.drugbank.com/drugs/DB07688
    Experimental

    Synonyms: 4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE
  7. Drug

    3-(3-aminophenyl)-N-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amine

    go.drugbank.com/drugs/DB07698
    Experimental

    Synonyms: 3-(3-aminophenyl)-N-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amine
  8. Drug

    LDN-193189

    go.drugbank.com/drugs/DB18051
    Experimental

    Synonyms: 4-(6-(4-(piperazin-1-yl)phenyl_pyrazolo[1,5-a]pyrimidin-3-yl)quinoline, Quinoline, 4-(6-(4-(1-piperazinyl)phenyl)pyrazolo(1,5-a)pyrimidin-3-yl)-Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Vidutolimod

    go.drugbank.com/drugs/DB17500
    Investigational

    Vidutolimod is a Toll-like receptor 9 (TLR9) agonist. It is an investigational cancer vaccine.

    Synonyms: Dna, d(g-g-g-g-g-g-g-g-g-g-g-a-c-g-a-t-c-g-t-c-g-g-g-g-g-g-g-g-g-g), Cmp-001 component cpg-a oligodeoxynucleotide tlr9 agonist
  10. Drug

    Evorpacept

    go.drugbank.com/drugs/DB17573
    Investigational

    Evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).

    Synonyms: A CD47-binding, fusion protein containing a high affinity engineered D1 domain of human signal regulatory protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domain