LDN-193189

DB18051ExperimentalSmall molecule

LDN-193189: Overview.

Mechanism: Pharmacologically active on Activin receptor type-1, Bone morphogenetic protein receptor type-1A, and Bone morphogenetic protein receptor type-1B
Curator reviewed
Formula / weight: C₂₅H₂₂N₆ · 406.493 g/mol (avg)
Also known as: 4-(6-(4-(piperazin-1-yl)phenyl_pyrazolo[1,5-a]pyrimidin-3-yl)quinoline · Quinoline, 4-(6-(4-(1-piperazinyl)phenyl)pyrazolo(1,5-a)pyrimidin-3-yl)-
Code names: LDN-193189

Resolves to

Compound

Structure

InChIKeyCDOVNWNANFFLFJ-UHFFFAOYSA-NSMILESC1CN(CCN1)C1=CC=C(C=C1)C1=CN2N=CC(=C2N=C1)C1=CC=NC2=CC=CC=C12

Targets

What you can answer from here — as of August 30, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with LDN-193189, and which of those have an active Phase 3 trial?

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