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Displaying results 4401 - 4410 of 7018 in total
  1. Drug

    Topiroxostat

    go.drugbank.com/drugs/DB01685
    Investigational

    While [DB00437] is considered a first-line therapy in treating hyperuricemic conditions, it is often associated with side effects and ineffective in reducing uric acid levels under recommended dosing regimens … Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout.

  2. Drug

    Morniflumate

    go.drugbank.com/drugs/DB09285
    Investigational

    Morniflumate is a non-steroidal anti-inflammatory drug with antipyretic properties. It is the morpholinoethyl ester of niflumic acid [L1496].

  3. Drug

    Carmofur

    go.drugbank.com/drugs/DB09010
    ApprovedWithdrawn

    Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.

  4. Drug

    Oremepermin alfa

    go.drugbank.com/drugs/DB27148
    Investigational

    Oremepermin alfa is a recombinant human hepatocyte growth factor (isoform 3) and glycoprotein composed of an α-chain and a β-chain.[L54006] It is produced in CHO cells.[L54006]

  5. Drug

    Stearyl alcohol

    go.drugbank.com/drugs/DB15953
    Investigational

    Mixtures: Gel
  6. Drug

    Brolucizumab

    go.drugbank.com/drugs/DB14864
    ApprovedInvestigational

    Brolucizumab, also known as RTH258 or ESBA1008,[A187211] is a monoclonal antibody indicated to treat neovascular age related macular degeneration.

  7. Drug

    RR001

    go.drugbank.com/drugs/DB17369
    Investigational

    (AD-PC sTRAIL). … RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand

  8. Drug

    HMI-203

    go.drugbank.com/drugs/DB18520
    Investigational

    It consists of a recombinant adeno-associated virus (AAV) serotype HSC15 (rAAVHSC15) encoding human iduronate-2-sulfatase (hIDS). … HMI-203 is an investigational gene therapy developed by Homology Medicines, Inc.

  9. Drug

    Clevidipine

    go.drugbank.com/drugs/DB04920
    ApprovedInvestigational

    Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.

  10. Drug

    Conestat alfa

    go.drugbank.com/drugs/DB09228
    Approved

    C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. … Marketed as the product Ruconest (FDA), this drug is indicated for the treatment of acute attacks of hereditary angioedema (HAE) due to C1 esterase inhibitor deficiency in adults.