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Displaying results 4421 - 4430 of 7059 in total
  1. Drug

    Tubercidin

    go.drugbank.com/drugs/DB03172
    Experimental

    An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids

    Synonyms: Sparsomycin A
  2. Drug

    Nabilone

    go.drugbank.com/drugs/DB00486
    ApprovedInvestigational

    From a pharmacological perspective, Cannabis' diverse receptor profile explains its potential application for such a wide variety of medical conditions. … Nabilone is a racemate consisting of the (S,S) and the (R,R) isomers.

  3. Drug

    Somatrogon

    go.drugbank.com/drugs/DB14960
    ApprovedInvestigational

    [A241485] Somatrogon was produced in Chinese Hamster Ovary (CHO) cells using recombinant DNA technology. … Somatrogon is a long-acting recombinant human growth hormone.

  4. Drug

    Concizumab

    go.drugbank.com/drugs/DB12820
    ApprovedInvestigational

    [L52043] Concizumab-mtci (Alhemo) was approved by the FDA in December 2024 for use in patients with hemophilia A or B with inhibitors. … Concizumab is a humanized IgG4 monoclonal antibody targeting the Kunitz-2 domain of tissue factor pathway inhibitor (TFPI), a key regulator of the coagulation cascade.

  5. Drug

    EA-2353

    go.drugbank.com/drugs/DB18506
    Investigational

    EA-2353 is a small molecule inhibitor of kinase mediators of the Wnt pathway.

  6. Drug

    Methyl-D9-choline

    go.drugbank.com/drugs/DB12628
    Investigational

    Methyl-D9-choline is under investigation in clinical trial NCT01807910 (ER Stress in NAFLD).

  7. Drug

    AZD-2836

    go.drugbank.com/drugs/DB06031
    Investigational

    AZD-2836 is an inhibitor of the nonstructural protein 5A (NS5A).[A264853] The drug is being investigated for treatment of hepatitis C because AZD-2836 has in vitro anti-HCV activity.[A264858]

  8. Drug

    APT20TTMG

    go.drugbank.com/drugs/DB32869
    Experimental

    APT20TTMG is a synthetic DNA that modulates U1 small nuclear ribonucleoprotein misassembly.

  9. Drug

    Telotristat ethyl

    go.drugbank.com/drugs/DB12095
    Approved

    Telotristat ethyl is a prodrug of telotristat that was approved by the FDA in March 2017 as Xermelo. … [L43342] It was previously referred to as telotristat etiprate, the hippurate salt form; however, the FDA recommends the use of the name of the neutral form rather than that of the salt.

  10. Drug

    TOP-1288

    go.drugbank.com/drugs/DB14839
    Investigational

    TOP-1288 is under investigation in clinical trial NCT02888379 (Phase 2a Study to Evaluate the Safety/Tolerability and Efficacy of TOP1288 200 mg Rectal Solution Once Daily for 4 Weeks in Ulcerative Colitis