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Displaying results 4461 - 4470 of 10000 in total
  1. Drug

    Rapacuronium

    go.drugbank.com/drugs/DB04834
    ApprovedWithdrawn

    Rapacuronium was withdrawn in 2001 in many countries due to risk of fatal bronchospasm.

  2. Drug

    Beinaglutide

    go.drugbank.com/drugs/DB15072
    Investigational

    Beinaglutide is under investigation in clinical trial NCT03829891 (Study for Beinaglutide Versus Glargine Therapy in Glycemic Variability of Type 2 Diabetes Mellitus).

    Categories: Drugs Used in Diabetes, Glucagon-like peptide-1 (GLP-1) analogues
  3. Drug

    Ixabepilone

    go.drugbank.com/drugs/DB04845
    ApprovedInvestigational

    Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. … Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. Ixabepilone is a semisynthetic analogue of epothilone B.

    Synonyms: Azaepothilone B, Aza-epothilone BCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  4. Drug

    ND1251

    go.drugbank.com/drugs/DB05132
    Experimental

    ND1251 is an orally active phosphodiesterase-4 (PDE4) inhibitor, a mechanism clinically proven to play a role in alleviating symptoms of depression. … ND1251 is a very potent compound with a large safety margin.

  5. Drug

    Glyceryl laurate

    go.drugbank.com/drugs/DB16635
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Methylisothiazolinone

    go.drugbank.com/drugs/DB15884
    Investigational

    Synonyms: N-Methylisothiazolin-3-one, 2-Methyl-4-isothiazolin-3-oneCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  7. Drug

    HZT-501

    go.drugbank.com/drugs/DB05369
    Investigational

    It has entered Phase 3 clinical trials in March 2007 for reduction of the risk of development of ibuprofen-associated upper gastrointestinal (i.e., gastric and/or duodenal) ulcers. … HZT-501 is under investigation by Horizon Therapeutics, Inc., a privately held biopharmaceutical company.

  8. Drug

    Acadesine

    go.drugbank.com/drugs/DB04944
    Investigational

    It is being developed jointly by PeriCor and Schering-Plough. Acadesine has been granted Orphan Drug Designation for B-CLL in the EU. … Acadesine (AICA-riboside) is a purine nucleoside analog with anti-ischemic properties that is currently being studied (Phase 3) for the prevention of adverse cardiovascular outcomes in patients undergoing

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    MIV-701

    go.drugbank.com/drugs/DB05736
    Experimental

    MIV-701 is a selective, potent inhibitor of the protease Cathepsin K. It is developed for the treatment of osteoporosis.

  10. Drug

    Piroximone

    go.drugbank.com/drugs/DB19750
    Experimental

    Piroximone is a small molecule drug. Piroximone has a monoisotopic molecular weight of 217.09 Da.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring