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Ceforanide
go.drugbank.com/drugs/DB00923ApprovedIts activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. … Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species
Synonyms: 7-[O-(aminomethyl)phenylacetamido]-3-[[[1-(carboxymethyl)-1H-tetrazol-5-yl]thio]methyl]-3-cephem-4-carboxylic acidBleomycin
go.drugbank.com/drugs/DB00290ApprovedInvestigationalA complex of related glycopeptide antibiotics from <i>Streptomyces verticillus</i> consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). … It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Products: BLEOMICINA 15 U VIAL, BLEOLEM 15 IU LIYOFILIZE TOZMacozinone
go.drugbank.com/drugs/DB14821InvestigationalMacozinone is under investigation in clinical trial NCT03036163 (Phase 1 Study of PBTZ169).
Categories: Drugs for Treatment of TuberculosisTedisamil
go.drugbank.com/drugs/DB06200ExperimentalTedisamil (planned trade name Pulzium) is an investigational drug for atrial fibrillation and atrial flutter.
Categories: Compounds used in a research, industrial, or household settingIdoxuridine
go.drugbank.com/drugs/DB00249ApprovedWithdrawnAn analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Synonyms: IdU, 1-beta-D-2'-Deoxyribofuranosyl-5-iodouracilInternational brands: Oftan IDUHexobendine
go.drugbank.com/drugs/DB13265ApprovedIt has not been approved in the United States or the United Kingdom, but has been used widely in Austria and Germany [T478].
Categories: Vasodilators Used in Cardiac DiseasesMBO7133
go.drugbank.com/drugs/DB04999ExperimentalHowever, araC is only slowly converted to araCTP in the liver or in primary liver tumors due to low levels of an enzyme in the liver that is required for the conversion of araC to araCMP, the first step … Higher doses of araC cannot be used to overcome this limitation due to bone marrow toxicity resulting from rapid activation in that tissue.
Diloxanide
go.drugbank.com/drugs/DB08792ExperimentalAlthough it is not currently approved for use in the United States, it was approved by a CDC study in the treatment of 4,371 cases of Entamoeba histolytica from 1977 to 1990. … Diloxanide (as [Diloxanide furoate]) is an anti-protozoal drug used in the treatment of Entamoeba histolytica and some other protozoal infections.
Isoflavone
go.drugbank.com/drugs/DB12007ApprovedInvestigationalWithdrawnWhile existing data are consistent or inadequate in supporting most of the suggested health benefits of consuming soy proteins and isoflavones [A33099], the trials investigating isoflavone as a potential … The clinical benefits of soy proteins have been studied and demonstrated for many years, with some evidence of soy products associated with a reduced incidences of coronary heart disease, atherosclerosis
Synonyms: 3-phenyl-4H-1-benzopyran-4-oneSaralasin
go.drugbank.com/drugs/DB06763ExperimentalCategories: Agents Acting on the Renin-Angiotensin System