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Imolamine
go.drugbank.com/drugs/DB09284InvestigationalIt is developed under the brand name Coremax by Novartis consumer health SA.
Categories: Vasodilators Used in Cardiac DiseasesDistearyldimonium
go.drugbank.com/drugs/DB14143ApprovedWithdrawnCategories: Compounds used in a research, industrial, or household settingGlycocholic acid
go.drugbank.com/drugs/DB02691InvestigationalIt acts as a detergent to solubilize fats for absorption and is itself absorbed.
Categories: N-substituted Glycines, Compounds used in a research, industrial, or household settingSynonyms: N-choloylglycineNirogacestat
go.drugbank.com/drugs/DB12005ApprovedInvestigationalIt was previously granted breakthrough therapy, fast track, and orphan drug designations for the treatment of desmoid tumors, and the final approval was based on positive results obtained in the Phase … Desmoid tumors are typically characterized by aberrant activation in Notch signaling.
UCB-1184197
go.drugbank.com/drugs/DB05092InvestigationalIt is considered a small-molecule prodrug. CDP323 was originally developed by the British biopharmaceutical company Celltech plc. … CDP323 is an antagonist of the _vascular cell adhesion molecule 1_ (VCAM-1) binding to alpha4-integrins (other adhesion molecules), a process thought to be implicated in the pathophysiology of Multiple
Chloroxine
go.drugbank.com/drugs/DB01243ApprovedWithdrawnChloroxine is a compound used in some shampoos for the treatment of dandruff and seborrheic dermatitis of the scalp.
Enmetazobactam
go.drugbank.com/drugs/DB18716ApprovedInvestigational[A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA on February 23, 2024, for the treatment of complicated urinary tract infections. … [A263266] Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious
Technetium Tc-99m etidronate
go.drugbank.com/drugs/DB09411ApprovedCategories: Compounds used in a research, industrial, or household settingArylacenamide
go.drugbank.com/drugs/DB05792ExperimentalIt is a dual agent with both immunomodulatory and antiproliferative activities. … Arylacenamide (SR31747) is a peripheral [sigma] ligand that binds four proteins in human cells, i.e. SRBP-1, [sigma]-2, HSI and its relative SRBP-2.
AI-850
go.drugbank.com/drugs/DB05842ExperimentalAI-850 is a Cremophor(R)-free formulation of paclitaxel, the active ingredient in Taxol(R), a product used to treat a variety of solid tumors.