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Displaying results 441 - 450 of 8515 in total
  1. Drug

    Capmatinib

    go.drugbank.com/drugs/DB11791
    ApprovedInvestigational

    STAT3, PI3K/ATK, and RAS/MAPK. … [L13380] As this indication was granted under an accelerated approval, its continued approval is contingent upon verification of capmatinib's benefit in confirmatory trials.

  2. Drug

    Rocuronium

    go.drugbank.com/drugs/DB00728
    ApprovedInvestigational

    [Sugammadex] is a γ-cyclodextrin derivative that has been introduced as a novel agent to reverse the action of rocuronium. … The drug is associated with the risk of developing allergic reactions in some high-risk patients, such as those with asthma.

  3. Drug

    Levopropoxyphene

    go.drugbank.com/drugs/DB06793
    ApprovedWithdrawn

    It was sold as an antitussive, but it was removed from the market in the 70s.[T133] Levopropoxyphene was developed by Lilly and FDA approved on March 21st, 1962. … This drug presented different dosages and it was administered as a capsule or suspension.

  4. Drug

    Pivopril

    go.drugbank.com/drugs/DB19854
    Experimental

    The usage of the INN stem '-pril' in the name indicates that Pivopril is a angiotensin-converting enzyme inhibitor. Pivopril has a monoisotopic molecular weight of 329.17 Da.

  5. Drug

    Utibapril

    go.drugbank.com/drugs/DB20306
    Experimental

    The usage of the INN stem '-pril' in the name indicates that Utibapril is a angiotensin-converting enzyme inhibitor. Utibapril has a monoisotopic molecular weight of 449.2 Da.

  6. Drug

    Alacepril

    go.drugbank.com/drugs/DB21364
    Experimental

    The usage of the INN stem '-pril' in the name indicates that Alacepril is a angiotensin-converting enzyme inhibitor. Alacepril has a monoisotopic molecular weight of 406.16 Da.

  7. Drug

    Pentopril

    go.drugbank.com/drugs/DB21436
    Experimental

    The usage of the INN stem '-pril' in the name indicates that Pentopril is a angiotensin-converting enzyme inhibitor. Pentopril has a monoisotopic molecular weight of 333.16 Da.

  8. Drug

    Torasemide

    go.drugbank.com/drugs/DB00214
    ApprovedInvestigational

    [A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent.[A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257]

  9. Drug

    Carbamazepine

    go.drugbank.com/drugs/DB00564
    ApprovedInvestigational

    [L1335] Interestingly, carbamazepine was the first anticonvulsant used to treat individuals with bipolar disorder.[A180319] … It was initially approved by the FDA in 1965.[A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1.

  10. Drug

    Ketotifen

    go.drugbank.com/drugs/DB00920
    ApprovedInvestigational

    It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and [azatadine]. … [A231204] Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis.