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Displaying results 441 - 450 of 10000 in total
  1. Drug

    Dacarbazine

    go.drugbank.com/drugs/DB00851
    ApprovedInvestigational

    An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). … Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.

    Synonyms: 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide, 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamideCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index
  2. Drug

    Aminopterin

    go.drugbank.com/drugs/DB08878
    ApprovedWithdrawn

    In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment of psoriasis. … Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia.

    Synonyms: N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid, 4-amino-4-deoxypteroylglutamateCategories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Allylestrenol

    go.drugbank.com/drugs/DB01431
    Investigational

    A synthetic steroid with progestational activity. … notably not in the United States or Canada.

    Synonyms: 17α-allylestr-4-en-17β-ol, 3-deketo-17α-allyl-19-nortestosteroneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Tivanisiran

    go.drugbank.com/drugs/DB19105
    Investigational

    Tivanisiran is under investigation in clinical trial NCT03108664 (HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED)).

    Synonyms: Rna, (a-a-g-c-g-c-a-u-c-u-u-c-u-a-c-u-u-c-a), complex with rna (u-g-a-a-g-u-a-g-a-a-g-a-u-g-c-g-c-u-u) (1:1)
  5. Drug

    Recombinant botulinum A/B vaccine

    go.drugbank.com/drugs/DB17830
    Investigational

    Synonyms: rBV A/B, Recombinant botulinum A/B vaccine
  6. Drug

    4-Carboxy-4-Aminobutanal

    go.drugbank.com/drugs/DB04388
    Experimental

    Synonyms: 4-Carboxy-4-Aminobutanal
  7. Drug

    4-PIPERIDIN-4-YLBUTANAL

    go.drugbank.com/drugs/DB04654
    Experimental

    Synonyms: 4-PIPERIDIN-4-YLBUTANAL
  8. Drug

    Dihydrostreptomycin

    go.drugbank.com/drugs/DB11512
    ApprovedVet approvedWithdrawn

    Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity.

    Synonyms: N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-a-L-glucopyranosyl]-3-C-(hydroxymethyl)-a-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine, N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-(hydroxymethyl)-α-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
  9. Drug

    Modified Cholera toxin A subunit

    go.drugbank.com/drugs/DB18556
    Experimental

    Synonyms: Modified Cholera toxin A subunit
  10. Drug

    Propanoyl-CoA

    go.drugbank.com/drugs/DB02912
    Experimental

    Synonyms: S-Propionyl-coenzym-A, S-propanoyl-coenzyme ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring