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Displaying results 441 - 450 of 10000 in total
  1. Drug

    ATX-101

    go.drugbank.com/drugs/DB05780
    Investigational

    ATX-101 (medical), sodium deoxycholate for subcutaneous injection, is being evaluated as a treatment for the reduction of localized fat deposits. … As a naturally occurring component of the human body, deoxycholate is considered a ‘biocompatible’ detergent that solubilizes fat in the small intestine.

  2. Drug

    alpha-Tocopherol succinate

    go.drugbank.com/drugs/DB14001
    ApprovedNutraceuticalVet approved

    , males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males … The recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months

    Mixtures: Prev-Rx, Ni-C-E-LE PlusCategories: Vitamin E, Heterocyclic Compounds, 1-Ring
  3. Target

    Splicing factor 3B subunit 1

    go.drugbank.com/bio_entities/BE0009359
    TargetHumans

    The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA … Also acts as a component of the minor spliceosome, which is involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077, PubMed:33509932).

    Synonyms: Pre-mRNA-splicing factor SF3b 155 kDa subunit
  4. Drug

    AGRO100

    go.drugbank.com/drugs/DB04998
    Investigational

    Pre-clinical testing demonstrates that the AGRO100 inhibition of nucleolin function produces anti-cancer effects against multiple types of the disease, including lung, prostate, breast, cervical, and colon … Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell.

  5. Drug

    Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10788
    ApprovedInvestigational

    Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) is a vaccine that contains inactivated acellular pertussis antigen that is isolated from Bordetella pertussis culture.

    Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, 3 ANTIGENProducts: PERTAGEN® SUSPENSION FOR INJECTION 0.5 ML/DOSE
  6. Target

    Serine/threonine-protein kinase PRP4 homolog

    go.drugbank.com/bio_entities/BE0009527
    TargetHumans

    Connects chromatin mediated regulation of transcription and pre-mRNA splicing (PubMed:12077342). … Associates with U5 snRNP and NCOR1 deacetylase complexes which may allow a coordination of pre-mRNA splicing with chromatin remodeling events involved in transcriptional regulation (PubMed:12077342).

    Synonyms: PRP4 pre-mRNA-processing factor 4 homolog
  7. Drug

    TG-100801

    go.drugbank.com/drugs/DB05075
    Investigational

    TG100801 is a topically applied kinase inhibitor in macular degeneration patients.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    GFT14

    go.drugbank.com/drugs/DB05061
    Experimental

    The risks of medical interaction are weak and GFT14 may be easily combined with statins or other antidiabetic molecules (glitazones). … GFT14 is a new class of medicaction for treatment of cardiometabolic disease.

  9. Drug

    Human vaccinia virus immune globulin

    go.drugbank.com/drugs/DB14112
    ApprovedInvestigational

    Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine … Most compounds used currently are intravenous formulations, which contain no preservatives - unlike prior intramuscular compounds which contained thiomersal, a mercury derivative preservative that could

    Categories: Immunoglobulin G, Human Immunoglobulin G
  10. Drug

    Denufosol

    go.drugbank.com/drugs/DB04983
    Investigational

    A new drug application (NDA) was filed with the FDA in 2011, however, the second phase III clinical trial showed a lack of improvement in lung function for cystic fibrosis patients taking denufosol. … Denufosol was an inhaled drug used for the treatment of cystic fibrosis (CF), showing various improvements in lung function during a phase III clinical trial.

    Categories: Heterocyclic Compounds, 1-Ring