Search
Cycloserine
go.drugbank.com/drugs/DB00260ApprovedInvestigationalAntibiotic substance produced by Streptomyces garyphalus.
Categories: Heterocyclic Compounds, 1-RingSynonyms: D-4-amino-3-isoxazolidone, D-4-amino-3-isoxazolidinoneCromoglicic acid
go.drugbank.com/drugs/DB01003ApprovedInvestigationalIt is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack. … A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.
Synonyms: 5-[3-(2-carboxy-4-oxo-4H-5-chromenyloxy)-2-hydroxypropoxy]-4-oxo-4H-2-chromenecarboxylic acidMixtures: OSMOCROM-N ®Aminobenzoic acid
go.drugbank.com/drugs/DB02362ApprovedWithdrawnA member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Synonyms: 1-Amino-4-carboxybenzene, 4-aminobenzoateMixtures: Multi B Complex Plus 500mg Vitamin C Tablets, VIVA B COMPLEX TABLETNicotine
go.drugbank.com/drugs/DB00184ApprovedInvestigationalNicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. … Nicotine is also important medically because of its presence in tobacco smoke.
Synonyms: (S)-3-(N-methylpyrrolidin-2-yl)pyridine, 3-(N-methylpyrollidino)pyridineCategories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine Dependencetrans-2-hydroxycinnamic acid
go.drugbank.com/drugs/DB01650ExperimentalSynonyms: o-Coumaric acid, 2-Coumaric acidInfliximab
go.drugbank.com/drugs/DB00065ApprovedInvestigationalThere are currently two biosilimars of infliximab available in the US market that demonstrate a high degree of similarity to the reference product, Remicade. … Its hyperactivity and enhanced signalling pathways can be observed in inflammatory diseases where it activates further pro-inflammatory cascades.
Synonyms: IMMUNOGLOBULIN G (HUMAN-MOUSE MONOCLONAL CA2 HEAVY CHAIN ANTI-HUMAN TUMOR NECROSIS FACTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CA2 LIGHT CHAIN, DIMERProducts: INFLECTRA 100MG PLV F E KO, REMICADE 100MG PULV F E KOKetazolam
go.drugbank.com/drugs/DB01587ApprovedWithdrawnKetazolam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. Ketazolam is not approved in Canada or America.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Loftran Cap 30mgLesinurad
go.drugbank.com/drugs/DB11560ApprovedWithdrawnMarketed as the product Zurampic, it is indicated for use in combination with a xanthine oxidase inhibitor for the treatment of hyperuricemia associated with gout in patients who have not achieved target … Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout.
Synonyms: {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acidCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersFerrous ascorbate
go.drugbank.com/drugs/DB14490ApprovedWithdrawnSynonyms: Iron(2+) L-ascorbate, L-Ascorbic acid, iron complexCategories: Compounds used in a research, industrial, or household settingAmobarbital
go.drugbank.com/drugs/DB01351ApprovedIllicitA barbiturate with hypnotic and sedative properties (but not antianxiety). … Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: 5-ethyl-5-(3-methylbutyl)barbituric acid, 5-ethyl-5-(3-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione