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Displaying results 441 - 450 of 10000 in total
  1. Drug

    G100

    go.drugbank.com/drugs/DB17244
    Investigational

    Synonyms: Glucopyranosyl Lipid A Stable Emulsion
  2. Drug

    Padnarsertib

    go.drugbank.com/drugs/DB19243
    Investigational

    Synonyms: Pak4-in-1, 2-propenamide, 3-(6-amino-3-pyridinyl)-n-((5-(4-((4,4-difluoro-1-piperidinyl)carbonyl)phenyl)-7-(4-fluorophenyl)-2-benzofuranyl)methyl)-, (2e)-Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    N-acetyltyrosine

    go.drugbank.com/drugs/DB11102
    ApprovedInvestigational

    N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. [DB00135] is a non-essential amino acid with a polar side group. … It is typically administered as a source of nutritional support where oral nutrition is inadequate or cannot be tolerated.

    Mixtures: Aminosyn II 7% M In 10% Dextrose(dual Chamber), Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)Synonyms: Melanowhite-A, L-N-acetyltyrosine
  4. Drug

    Ginsenoside Rg1

    go.drugbank.com/drugs/DB06750
    ExperimentalNutraceutical

    Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). … Rg1 Appears to be most abundant in Panax ginseng (Chinese/Korean Ginseng). It improves spatial learning and increase hippocampal synaptophysin level in mice, plus demonstrates estrogen-like activity.

    Synonyms: Panaxoside A, Ginsenoside A2
  5. Drug

    N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE

    go.drugbank.com/drugs/DB08629
    Experimental

    Synonyms: N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
  6. Drug

    Efepoetin alfa

    go.drugbank.com/drugs/DB19197
    Investigational

    Efepoetin alfa is under investigation in clinical trial NCT04155125 (A Study of Efepoetin Alfa in Treating Anaemia Associated With Chronic Kidney Diseases Patient).

    Synonyms: in chinese hamster ovary (cho) cells, glycoform al, Human erythropoietin (epoetin alfa) fused to a hybrid human immunoglobulin (ig), consisting of the fc fragment of the igg4 fused to the hinge and amino-terminus of the igd heavy chain isotype 2, produced
  7. Drug

    Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate

    go.drugbank.com/drugs/DB01868
    Experimental

    Synonyms: Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate
  8. Drug

    Exagamglogene autotemcel

    go.drugbank.com/drugs/DB15572
    ApprovedInvestigational

    [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease in HbS. … Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe

    Synonyms: gene editing consisting of a guide RNA (gRNA), Autologous CD34+ cells isolated from mobilised peripheral blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated
  9. Drug

    Daplusiran

    go.drugbank.com/drugs/DB19331
    Investigational

    Daplusiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis … B (CHB)).

    Synonyms: RNA, (AM-SP-(2'-DEOXY-2'-FLUORO)G-SP-AM-SP-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY-2'-FLUORO)A-UM-(2'-DEOXY-2'-FLUORO)U-GM-(2'-DEOXY-2'-FLUORO)A-GM-(2'-DEOXY-2'-FLUORO)A-GM-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY, -2'-FLUORO)G-UM-(2'-DEOXY-2'-FLUORO)C-CM-AM-SP-CM),
  10. Drug

    Obecabtagene autoleucel

    go.drugbank.com/drugs/DB17362
    ApprovedInvestigational

    Obecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19. … [A265040,A265045] It works by targeting B-cell-specific CD19 surface markers present on malignant B cells.

    Synonyms: A CHIMERIC ANTIGEN RECEPTOR (CAR) CONSISTING O, AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) OBTAINED BY APHERESIS TRANSDUCED EX VIVO WITH A NON-REPLICATING, SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODINGCategories: Genetically-modified Autologous T Cells, CD19-Directed Genetically Modified Autologous T-cell Immunotherapies