Padnarsertib

DB19243InvestigationalSmall molecule

Padnarsertib: Overview.

Chemical structure of Padnarsertib
Formula / weight
C35H29F3N4O3 · 610.637 g/mol (avg)
Also known as
2-propenamide, 3-(6-amino-3-pyridinyl)-n-((5-(4-((4,4-difluoro-1-piperidinyl)carbonyl)phenyl)-7-(4-fluorophenyl)-2-benzofuranyl)methyl)-, (2e)- · Pak4-in-1
Code names
KPT-9274

Resolves to

Compound
UNII9T56TV18X7CAS1643913-93-2ChEMBLCHEMBL4297467
Structure
InChIKeyMRFOPLWJZULAQD-SWGQDTFXSA-NSMILESNC1=CC=C(\C=C\C(=O)NCC2=CC3=CC(=CC(=C3O2)C2=CC=C(F)C=C2)C2=CC=C(C=C2)C(=O)N2CCC(F)(F)CC2)C=N1
Targets
O96013PAK4

What you can answer from here — as of April 23, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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3Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Padnarsertib, and which of those have an active Phase 3 trial?

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