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Displaying results 4491 - 4500 of 4635 in total
  1. Drug

    Lecozotan

    go.drugbank.com/drugs/DB12540
    Investigational

    Lecozotan has been used in trials studying the treatment of Alzheimer Disease.

    Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT1A Receptor Antagonists
  2. Drug

    Nelotanserin

    go.drugbank.com/drugs/DB12555
    Investigational

    It is a highly selective antagonist at the 5-HT2A serotonin receptor. It increases non-REM sleep, the most restorative phase of the sleep cycle, without sacrificing REM or dream sleep.

  3. Drug

    L-deprenyl-D2 C-11

    go.drugbank.com/drugs/DB12650
    Experimental

    L-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers).

    Synonyms: (11C)L-deprenyl-D2, L-deprenyl-D2 C-11
  4. Drug

    Eltoprazine

    go.drugbank.com/drugs/DB12883
    Investigational

    Eltoprazine has been used in trials studying the treatment of Schizophrenia and Cognitive Impairment.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor Antagonists
  5. Drug

    Oprelvekin

    go.drugbank.com/drugs/DB00038
    ApprovedInvestigationalWithdrawn

    Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced in Escherichia coli (E. coli) by recombinant DNA technology.

  6. Drug

    Digoxin Immune Fab (Ovine)

    go.drugbank.com/drugs/DB00076
    Approved

    Digoxin Immune Fab is a sheep antibody (26-10) FAB fragment from sheep immunized with the digoxin derivative Digoxindicarboxymethylamine. It is used as an antidote for overdose of digoxin.

    Categories: Immunoglobulin G
  7. Drug

    N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide

    go.drugbank.com/drugs/DB06944
    Experimental

    N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide is a solid. This compound belongs to the naphthalenes. … The proteins that N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide targets include cyclin-A2 and cyclin-dependent kinase 2.

    Synonyms: N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide
  8. Drug

    GTS-21

    go.drugbank.com/drugs/DB05708
    Investigational

    GTS-21 (also known as DMBX-A), is a novel, small-molecule, orally active and selective alpha-7 nicotinic acetylcholine (nACh) receptor agonist that has demonstrated memory and cognition enhancement activity

  9. Drug

    TD-2749

    go.drugbank.com/drugs/DB05905
    Experimental

    TD-2749 is selective 5-HT4 agonists discovered by Theravance through the application of multivalent drug design in a drug discovery program dedicated to finding new medicines for GI motility disorders

  10. Drug

    SNS-032

    go.drugbank.com/drugs/DB05969
    Investigational