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Odanacatib
go.drugbank.com/drugs/DB06670InvestigationalOdanacatib is an inhibiter of cathepsin K which was originally developed be Merck & Co as a new treatment for osteoporosis [A19388]. … The drug made it to phase III trials before abandoned due to increased stroke.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPhenolsulfonphthalein
go.drugbank.com/drugs/DB13212ExperimentalPhenolsulfonphthalein or otherwise called phenol red is a pH indicator commonly used in cell biology laboratories. … Phenolsulfonphthalein is being investigated for use clinically due to its weak estrogen mimicking actions [A174964].
Categories: Compounds used in a research, industrial, or household settingIodoxamic acid
go.drugbank.com/drugs/DB13539ExperimentalRadiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.
Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, IodinatedADH-1
go.drugbank.com/drugs/DB05485InvestigationalADH-1 may have utility in a wide variety of cancers as N-cadherin is overexpressed in a variety of tumors. … Poorly differentiated, highly invasive carcinomas are characterized by over-expression of N-cadherin (as opposed to E-cadherin).
Synonyms: l-cysteinamide, n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-, cyclic (1-5)-disulfideDPI-221
go.drugbank.com/drugs/DB06121ExperimentalDPI-221 is an investigational drug and a selective agonist for the δ-opioid receptor.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-((.ALPHA.S)-.ALPHA.-((2S,5R)-2,5-DIMETHYL-4-(3-FLUOROBENZYL)-1-PIPERAZINYL)BENZYL)-N,N-DIETHYLBENZAMIDE, BENZAMIDE, N,N-DIETHYL-4-((S)-((2S,5R)-4-((3-FLUOROPHENYL)METHYL)-2,5-DIMETHYL-1-PIPERAZINYL)PHENYLMETHYL)-NOX-100
go.drugbank.com/drugs/DB05799InvestigationalNOX-100 is the first in a series of proprietary NO neutralizing compounds Medinox is developing to bind and inactivate NO, a simple gas molecule that is a key biological messenger in the body. … NOX-100 is the new nitric oxide (NO) neutralizing agent being developed by San Diego-based Medinox -- demonstrated its effectiveness and potential as a therapeutic to treat hemorrhagic shock.
Isoetharine
go.drugbank.com/drugs/DB00221ApprovedIsoetharine is a relatively selective beta-2 adrenergic agonist. It is a catechol-like agent. Isoetharine is a fast-acting bronchodilator used for emphysema, bronchitis and asthma.[A330]
Categories: Adrenergic beta-2 Receptor Agonists, Selective Beta 2-adrenergic AgonistsSulfobutylether-beta-cyclodextrin
go.drugbank.com/drugs/DB18607ExperimentalCategories: Compounds used in a research, industrial, or household setting4-Nitrophenyl Phosphate
go.drugbank.com/drugs/DB04214ExperimentalCategories: Compounds used in a research, industrial, or household settingSynonyms: 4-Nitrophenyl PhosphateHZT-501
go.drugbank.com/drugs/DB05369InvestigationalIt has entered Phase 3 clinical trials in March 2007 for reduction of the risk of development of ibuprofen-associated upper gastrointestinal (i.e., gastric and/or duodenal) ulcers. … HZT-501 is under investigation by Horizon Therapeutics, Inc., a privately held biopharmaceutical company.