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Displaying results 4571 - 4580 of 10000 in total
  1. Drug

    Darigabat

    go.drugbank.com/drugs/DB18966
    Investigational

    Darigabat is under investigation in clinical trial NCT05941442 (A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxybiphenyl-3-yl)-7h-imidazo(4,5-c)-pyridazine, 7h-imidazo(4,5-c)pyridazine, 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxy(1,1'-biphenyl)-3-yl)-
  2. Drug

    CT-179

    go.drugbank.com/drugs/DB17114
    Investigational

    Synonyms: 1-(2-(3-(3,4-dichlorophenyl)ureido)-6-methyl-pyrimidin-4-yl)-amino-3(dimethylamino)propane, Urea, n-(3,4-dichlorophenyl)-n'-(4-((3-(dimethylamino)propyl)amino)-6-methyl-2-pyrimidinyl)-
  3. Drug

    Platelet Activating Factor

    go.drugbank.com/drugs/DB02261
    Experimental

    Synonyms: 1-hexadecyl-2-acetyl-glycero-3-phosphocholine, PAF acetherCategories: P-glycoprotein inducers, P-glycoprotein substrates
  4. Drug

    Thalidomide

    go.drugbank.com/drugs/DB01041
    ApprovedInvestigationalWithdrawn

    A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. … Due to severe teratogenicity, pregnancy must be excluded before the start of treatment and patients must enrol in the THALIDOMID Risk Evaluation and Mitigation Strategy (REMS) program to ensure contraception

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline, α-N-phthalylglutaramide
  5. Drug

    Rosomidnar

    go.drugbank.com/drugs/DB17154
    Investigational

    Synonyms: (3'-5')d(c-a-c-g-c-a-c-g-c-g-c-a-t-c-c-c-c-g-c-c-c-g-t-g)
  6. Drug

    Efzofitimod

    go.drugbank.com/drugs/DB16453
    Investigational

    It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states. … Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody.

    Synonyms: Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein
  7. Drug

    Radium Ra-223 cation

    go.drugbank.com/drugs/DB14571
    Experimental

    Synonyms: Radium-223 ion(2+)
  8. Drug

    AGT-182

    go.drugbank.com/drugs/DB17630
    Investigational

    AGT-182 is an investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and a human insulin receptor monoclonal antibody.

    Synonyms: Recombinant human insulin receptor monoclonal antibody-fused iduronate 2-sulfatase
  9. Drug

    CD-16 NK-92 cells

    go.drugbank.com/drugs/DB17465
    Investigational

    Synonyms: NK-92 [CD16.158V, ER IL-2]
  10. Drug

    Aconiazide

    go.drugbank.com/drugs/DB17731
    Experimental

    Synonyms: Isonicotinic acid (2-(carboxymethoxy)benzylidene)hydrazide, Isonicotinic acid (o-(carboxymethoxy)benzylidene)hydrazideCategories: Heterocyclic Compounds, 1-Ring