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Hydralazine
go.drugbank.com/drugs/DB01275ApprovedInvestigational[T691] Hydralazine hydrochloride was FDA approved on 15 January 1953.[L8779] … [A186820,L8782,L8785] Hydralazine is no longer a first line therapy for these indications since the development of newer antihypertensive medications.
Synonyms: (1Z)-1(2H)-Phthalazinone hydrazone, Hydrazone 1(2H)-phthalazinoneMixtures: TRI NORMIN 50, Ser-Ap-EsNebivolol
go.drugbank.com/drugs/DB04861ApprovedInvestigational[A182594] Nebivolol was granted FDA approval on 17 December 2007.[L7985] … [A182579] Nebivolol and other beta blockers are generally not first line therapies as many patients are first treated with thiazide diuretics.
Mixtures: AMLONEB 10 MG/10 MG TABLET, 30 ADET, AMLONEB 10 MG/10 MG TABLET, 90 ADETCategories: Heterocyclic Compounds, 2-Ring, Adrenergic beta-1 Receptor AgonistsBaclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigationalAlthough originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977.
Products: BACLOFEN 10 MG/ 20 ML, Lioresal intrathekal 10 mg/20 ml - AmpulleVenlafaxine
go.drugbank.com/drugs/DB00285ApprovedInvestigational[A252065] Venlafaxine has been used as a first-line treatment for MDD, GAD, social anxiety disorder, and panic disorder in Canada for many years. … It was also considered a second-line treatment for obsessive-compulsive disorder (OCD).
Products: EFEXOR XR 37,5 MG MIKROPELLET KAPSUL, 10 ADET, VENLIFT ER 150 MG CAPSULECarbamazepine
go.drugbank.com/drugs/DB00564ApprovedInvestigationalIt was initially approved by the FDA in 1965.[A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. … Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia.
Products: TEGRETOL CR 200 MG TABLET, 20 ADET, KARAZEPIN 400 MG TABLET, 20 ADETFamotidine
go.drugbank.com/drugs/DB00927ApprovedInvestigationaldisease, famotidine was about 20 to 50 times more potent at inhibiting gastric acid secretion than [cimetidine] and eight times more potent than [ranitidine] on a weight basis. … Famotidine is a competitive histamine-2 (H<sub>2</sub>) receptor antagonist that works to inhibit gastric acid secretion.
Synonyms: (1-Amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide, 3-(((2-((Diaminomethylene)amino)-4-thiazolyl)methyl)thio)-N(sup 2)-sulfamoylpropionamidineMixtures: ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 2 ADET, TRIGAST 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 12 ADETAtenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigationalAtenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and received FDA approval in September, 1981. … [A235860,A235865] A meta-analysis of over 145,000 patients showed the risk of stroke in patients taking atenolol may depend on the age of the patient.
Synonyms: 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol, 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamideMixtures: TENORETIC 100 MG/25 MG FILM TABLET, 28 ADET, TENORETIC 50 MG/12.5 MG FILM TABLET, 28 ADETInosine pranobex
go.drugbank.com/drugs/DB13156ApprovedInosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Synonyms: Inosine-2-hydroxypropyldimethylammonium 4-acetamidobenzoate (1:3)Categories: Heterocyclic Compounds, 2-RingNizatidine
go.drugbank.com/drugs/DB00585ApprovedA histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Categories: Heterocyclic Compounds, 1-RingSynonyms: N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamineBuprenorphine
go.drugbank.com/drugs/DB00921ApprovedIllicitInvestigationalVet approved[A186263,A186266,A186269] Buprenorphine acts as a partial mu-opioid receptor agonist with a high affinity for the receptor, but lower intrinsic activity compared to other full mu-opioid agonists such … Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.
Mixtures: Bupensan Duo 4 mg/1 mg-Sublingualtabletten, SUBOXONE 8 MG/2 MG DILALTI TABLET, 28 ADETCategories: Drugs Used in Opioid Dependence, Drugs Used in Addictive Disorders