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Displaying results 451 - 460 of 10000 in total
  1. Drug

    Terbinafine

    go.drugbank.com/drugs/DB00857
    ApprovedInvestigationalVet approved

    Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. … [A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992.[L9064]

    Synonyms: (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamineMixtures: Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4%, M-FURO MANT % 0.1 + % 1 KREM, 20G
  2. Drug

    Olanzapine

    go.drugbank.com/drugs/DB00334
    ApprovedInvestigational

    [A176996] Its chemical structure contains a thieno[2,3-b][1,5]benzodiazepine core, and has a methyl group attached to the piperazine ring. … Olanzapine is a thienobenzodiazepine derivative and an atypical or second-generation antipsychotic agent.

    Synonyms: 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepineInternational brands: Jolyon-MD
  3. Drug

    Cobicistat

    go.drugbank.com/drugs/DB09065
    ApprovedInvestigational

    Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered … Increasing systemic exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and a decreased side effect profile.

    Synonyms: 1,3-thiazol-5-ylmethyl [(2R,5R)-5-{[(2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamateMixtures: PREZCOBIX® TABLETAS RECUBIERTAS, GENVOYA ® TABLETAS RECUBIERTAS
  4. Drug

    Amsacrine

    go.drugbank.com/drugs/DB00276
    ApprovedInvestigationalWithdrawn

    Aminoacridine derivative that is a potent intercalating antineoplastic agent.

    Categories: Heterocyclic Compounds, 3-Ring, P-glycoprotein inhibitorsSynonyms: 4'-(9-Acridinylamino)methanesulfon-m-anisidide, 4'-(9-Acridinylamino)-3'-methoxymethanesulfonanilide
  5. Drug

    Tienilic acid

    go.drugbank.com/drugs/DB04831
    ApprovedWithdrawn

    Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension. … It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)

    Synonyms: (2,3-Dichloro-4-(2-thenoyl)phenoxy)acetic acid, 4-(2-Theonyl)-2,3-dichlorphenoxyessigsäureCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2C9 Inhibitors
  6. Drug

    Nevirapine

    go.drugbank.com/drugs/DB00238
    ApprovedInvestigational

    A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS.

    Synonyms: 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-oneMixtures: TRIVIRO LNS® LAMIVUDINA 150 MG NEVIRAPINA 200 MG ESTAVUDINA 40 MG, FAXIBON ® 40
  7. Drug

    4-(2-Amino-Ethoxy)-2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Amino]-but-3-Enoic Acid

    go.drugbank.com/drugs/DB03287
    Experimental

    Synonyms: 4-(2-Amino-Ethoxy)-2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Amino]-but-3-Enoic Acid
  8. Drug

    Clavulanic acid

    go.drugbank.com/drugs/DB00766
    ApprovedInvestigationalVet approved

    Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin] to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening

    Mixtures: AMOKSIKLAV 2X (SUSPENSION 457 MG/5 ML), Amoclanhexal 1 g (875 mg/125 mg) - FilmtablettenCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-Ring
  9. Drug

    2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE

    go.drugbank.com/drugs/DB07268
    Experimental

    Synonyms: 2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE
  10. Drug

    Sulfadiazine

    go.drugbank.com/drugs/DB00359
    ApprovedInvestigationalVet approved

    One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

    Synonyms: 4-amino-N-2-pyrimidinylbenzenesulfonamide, N(1)-2-PyrimidylsulfanilamideMixtures: SUFATRIM 48%w/w Premix, TMP/S-400 Medicated Premix Powder