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Forodesine
go.drugbank.com/drugs/DB06185Investigationalleukemia and cutaneous T-cell lymphoma. … Forodesine is a highly potent, orally active, rationally designed PNP inhibitor that has shown activity in preclinical studies with malignant cells and clinical utility against T-cell acute lymphoblastic
Synonyms: 1,4-Dideoxy-4-aza-1-(S)-(9-deazahypoxanthin-9-yl)-D-ribitol, (1S)-1,4-dideoxy-4-imino-(9-deazahypoxanthin-9-yl)-D-ribitolCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingTelitacicept
go.drugbank.com/drugs/DB18312InvestigationalSynonyms: (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY PROTEIN TNFRSF13B) HUMAN EXTRACELLULAR DOMAIN FRAGMENT (13-118)-PEPTIDE, (1-106) FUSION PROTEIN WITH HUMAN IMMUNOGLOBULIN G1Amikacin
go.drugbank.com/drugs/DB00479ApprovedInvestigationalVet approvedAmikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A. … [FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexSynonyms: D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-(4-AMINO-2-HYDROXY-1-OXOBUTYL)-2-DEOXY-, (S)-, 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin ACoenzyme F420
go.drugbank.com/drugs/DB03913ExperimentalSynonyms: N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-γ-L-glutamyl}-L-glutamate, coenzyme γ-F420-2Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-RingKTX-1001
go.drugbank.com/drugs/DB18171InvestigationalSynonyms: (S)-1-((R)-3-amino-1-(4-((6-amino-9H-purin-9-yl)methyl)-6-(2,5-difluoro-4-methoxyphenyl)pyridin-3-yl)piperidin-3-yl)-2,2-difluoroethan-1-olSalts: KTX-1001 D-tartrateD-Cysteine
go.drugbank.com/drugs/DB03201ExperimentalA thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
Salts: D-Cysteine hydrochloride monohydrateSynonyms: (S)-2-amino-3-mercaptopropanoic acid, (2S)-2-amino-3-mercaptopropanoic acidLevotofisopam
go.drugbank.com/drugs/DB19073InvestigationalLevotofisopam is under investigation in clinical trial NCT01519687 (Study of Levotofisopam 50 Mg Three Times a Day (TID) Administered for 7 Days on Hyperuricemia and Gout).
Synonyms: (s)-tofisopam, (-)-(5s)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepineCategories: Heterocyclic Compounds, 2-RingOxfendazole
go.drugbank.com/drugs/DB11446InvestigationalVet approvedOxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
Categories: Heterocyclic Compounds, 2-RingSynonyms: Fenbendazole S-oxide, 5-phenylsulfinyl-2-carbomethoxyaminobenzimidazoleTilpisertib
go.drugbank.com/drugs/DB18798InvestigationalSynonyms: 3-quinolinecarbonitrile, 6-(((s)-(1-bicyclo(1.1.1)pent-1-yl-1h-1,2,3-triazol-4-yl)(1,2-dihydro-2-methyl-1-oxo-5-isoquinolinyl)methyl)amino)-8-chloro-4-((2,2-dimethylpropyl)amino)-Tretamine
go.drugbank.com/drugs/DB14031ExperimentalToxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,4,6-tris(1-aziridinyl)-s-triazine, 2,4,6-tri(1-aziridinyl)-1,3,5-triazine