Oxfendazole

DB11446InvestigationalVet approvedSmall molecule

Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.

Chemical structure of Oxfendazole
Mechanism
Curator reviewed
Formula / weight
C15H13N3O3S · 315.347 g/mol (avg)
Also known as
Fenbendazole S-oxide · Fenbendazole sulfoxide · Fenbendazole sulphoxide · OFDZ
Code names
RS-8858

Resolves to

Compound
UNIIOMP2H17F9ECAS53716-50-0ChEMBLCHEMBL42442ChEBI35812KEGGD05291
Clinical / RWD
RxNorm32634
Structure
InChIKeyBEZZFPOZAYTVHN-UHFFFAOYSA-NSMILESCOC(=O)NC1=NC2=CC(=CC=C2N1)S(=O)C1=CC=CC=C1
Targets
P12931SRCP51617IRAK1

What you can answer from here — as of July 07, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
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1Drug interactionStructured to mechanism, not free text
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9Clinical trialsPhase, status and sponsor resolved per trial
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14+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Oxfendazole, and which of those have an active Phase 3 trial?

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