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MF-300
go.drugbank.com/drugs/DB32060InvestigationalAs a potential candidate for the treatment of sarcopenia, it has undergone phase 1 studies to evaluate safety, tolerability, and PK/PD characteristics.[A275368,L54983] … MF-300 is an investigational, first-in-class, small molecule inhibitor of 15-hydroxyprostaglandin dehydrogenase.
PF-03187207
go.drugbank.com/drugs/DB05746InvestigationalPF-03187207 is a nitric oxide-donating prostaglandin F2-alpha analogs for the potential treatment of glaucoma. … The development of abnormally high IOP, due to blockage or malfunction of systems controlling the amount of fluid in the eye, is believed to be one of the principal causes of glaucoma.
Eftansomatropin alfa
go.drugbank.com/drugs/DB18460Investigational[L48275] It is under investigation for the treatment of growth hormone deficiency. … Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment.
CIGB 300
go.drugbank.com/drugs/DB16464InvestigationalCIGB-300, is under investigation in clinical trials for its potential to treat various conditions, including NCT01639638 (recurrent and nonrecurrent condyloma) and NCT01639625 (squamous cell carcinoma
Categories: Experimental Unapproved Treatments for COVID-19Etynodiol
go.drugbank.com/drugs/DB13866ExperimentalWhile etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate (see [DB00823]), not etynodiol. … Etynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed.
Categories: Hormonal Contraceptives for Systemic UseSynonyms: (3β,17α)-19-Norpregn-4-en-20-yne-3,17-diolPradefovir mesylate
go.drugbank.com/drugs/DB05478InvestigationalPradefovir is undergoing phase II development for the treatment of chronic hepatitis B. … [Adefovir] (Hepsera) is an acyclic phosphonate analogue of adenine that is used to treat hepatitis B virus.
Fleroxacin
go.drugbank.com/drugs/DB04576ExperimentalFleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. Fleroxacin is not an inhibitor of CYP1A2.[A39048]
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UsePegademase
go.drugbank.com/drugs/DB00061ApprovedWithdrawnBovine adenosine deaminase derived from bovine intestine that has been extensively pegylated for extended serum half life.
Anti-SARS-CoV-2 REGN-COV2
go.drugbank.com/drugs/DB15691Investigational[L14306] Clinical trials for this drug started on June 11, 2020. … Anti-SARS-COV-2 REGN-COV2 is a combination of novel antibodies designed by Regeneron for both the prevention and treatment of SARS-COV-2, the virus that causes COVID-19.
Categories: Experimental Unapproved Treatments for COVID-19Paspalum notatum pollen
go.drugbank.com/drugs/DB10349ApprovedPaspalum notatum pollen is the pollen of the Paspalum notatum plant. Paspalum notatum pollen is mainly used in allergenic testing.
Mixtures: Mixture of Standardized and Non-Standardized Southeastern GrassesCategories: Non-Standardized Pollen Allergenic Extract