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BB 21217
go.drugbank.com/drugs/DB17373Investigational21217 is an anti-BCMA CAR T cell therapy that uses the same CAR molecule as [idecabtagene vicleucel] (bb2121), but adds the PI3K inhibitor bb007 during ex vivo culture to enrich the drug product (DP) for
RGX-501
go.drugbank.com/drugs/DB17639InvestigationalIt is being investigated for the treatment of homozygous familial hypercholesterolemia.[L46696]
Dabocemagene autoficel
go.drugbank.com/drugs/DB17878InvestigationalDeveloped by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.[L46797]
Viralym-C
go.drugbank.com/drugs/DB17975InvestigationalIt was granted FDA orphan designation in January 2017 and investigated for the treatment of CMV infection.[A260291, L47241]
DYNE-251
go.drugbank.com/drugs/DB18130InvestigationalIt is being investigated for the treatment of Duchenne muscular dystrophy (DMD) in patients who are amenable to exon 51 skipping.
BO-653
go.drugbank.com/drugs/DB19216InvestigationalBO-653 is under investigation in clinical trial NCT00055510 (A Blinded Study Conducted at Multiple Centers Evaluating Various Doses of an Investigational Agent (BO-653) Against Placebo, for Safety and
Barbital
go.drugbank.com/drugs/DB01483ExperimentalIllicitBarbital is also used in veterinary practice for central nervous system depression. Barbital is a schedule IV controlled drug.
Sibrotuzumab
go.drugbank.com/drugs/DB06474InvestigationalSibrotuzumab is a humanized monoclonal antibody directed against fibroblast activation protein (FAP). It is used to treat cancer.
Nicofetamide
go.drugbank.com/drugs/DB13531ExperimentalCategories: Drugs for Functional Gastrointestinal Disorders