Search

Displaying results 4621 - 4630 of 10000 in total
  1. Drug

    Vorasidenib

    go.drugbank.com/drugs/DB17097
    ApprovedInvestigational

    [A264209] It works by suppressing the levels of D-2-hydroxyglutarate (2-HG), an oncometabolite produced by mutant IDH1 and IDH2 isoforms. … Vorasidenib is a first-in-class dual isocitrate dehydrogenase-1 (IDH1) and isocitrate dehydrogenase-2 (IDH2) inhibitor.

    Synonyms: 1,3,5-triazine-2,4-diamine, 6-(6-chloro-2-pyridinyl)-n2,n4-bis((1r)-2,2,2-trifluoro-1-methylethyl)-Categories: Isocitrate Dehydrogenase 2 Inhibitor, Isocitrate dehydrogenase-2 (IDH2) Inhibitors
  2. Drug

    Tividenofusp alfa

    go.drugbank.com/drugs/DB17628
    ApprovedInvestigational

    Hunter syndrome is a rare, X-linked lysosomal storage disorder caused by a deficiency in the enzyme iduronate-2-sulfatase (IDS), which leads to the toxic accumulation of glycosaminoglycans (GAGs) throughout … Tividenofusp alfa is a recombinant human IDS fused to a monoclonal antibody that targets the human insulin receptor (HIR), utilizing receptor-mediated transcytosis to gain access to the central nervous

    Synonyms: Iduronate-2-sulfatase (human) fusion protein with immunoglobulin Fcab, anti-(human type 1 transferrin receptor) (synthetic human ?1-chain 2), (536?6?),(539?9?), human iduronate 2-sulfatase (IDS, ?
  3. Drug

    Nitrofurantoin

    go.drugbank.com/drugs/DB00698
    ApprovedInvestigationalVet approved

    [A179824] Nitrofurantoin is a second line treatment to [trimethoprim]/[sulfamethoxazole].[A179830] Nitrofurantoin was granted FDA approval on 6 February 1953.[L6895] … Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedione, N-(5-Nitrofurfurylidene)-1-aminohydantoin
  4. Drug

    Ergometrine

    go.drugbank.com/drugs/DB01253
    ApprovedInvestigational

    An ergot alkaloid with uterine and vascular smooth muscle contractile properties.

    Categories: Heterocyclic Compounds with 4 or More Rings, P-glycoprotein inhibitorsSynonyms: (6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((S)-2-hydroxy-1-methyl-ethyl)-amide, N-(2-Hydroxy-1-methylethyl)-D-(+)-lysergamide
  5. Drug

    [2-(5-Mercapto-[1,3,4]thiadiazol-2-ylcarbamoyl)-1-phenyl-ethyl]-carbamic acid benzyl ester

    go.drugbank.com/drugs/DB07987
    Experimental

    Synonyms: [2-(5-Mercapto-[1,3,4]thiadiazol-2-ylcarbamoyl)-1-phenyl-ethyl]-carbamic acid benzyl ester
  6. Drug

    (5S)-5-(3-AMINOPROPYL)-3-(2,5-DIFLUOROPHENYL)-N-ETHYL-5-PHENYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDE

    go.drugbank.com/drugs/DB08250
    Experimental

    Synonyms: (5S)-5-(3-AMINOPROPYL)-3-(2,5-DIFLUOROPHENYL)-N-ETHYL-5-PHENYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDE
  7. Drug

    1,2-Di-N-Pentanoyl-Sn-Glycero-3-Dithiophosphocholine

    go.drugbank.com/drugs/DB02225
    Experimental

    Synonyms: 1,2-Di-N-Pentanoyl-Sn-Glycero-3-Dithiophosphocholine
  8. Drug

    5-(3,3-Dihydroxypropeny)-3-Methoxy-Benzene-1,2-Diol

    go.drugbank.com/drugs/DB04449
    Experimental

    Synonyms: 5-(3,3-Dihydroxypropeny)-3-Methoxy-Benzene-1,2-Diol
  9. Drug

    PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE

    go.drugbank.com/drugs/DB07614
    Experimental

    Synonyms: PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE
  10. Drug

    [(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL

    go.drugbank.com/drugs/DB07906
    Experimental

    Synonyms: [(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL