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Displaying results 4651 - 4660 of 10000 in total
  1. Drug

    LI-301

    go.drugbank.com/drugs/DB05509
    Experimental

    LI 301 is an orally bio-available compound delivered in a fast melt mechanism with taste masking enabling it to be taken anytime without water. … This results in a slight dulling of sensation that can be used to treat premature ejaculation without interfering with normal sexual pleasure or orgasm.

  2. Drug

    Andrographolide

    go.drugbank.com/drugs/DB05767
    Investigational

    The herb has an extensive history of use in TCM for the treatment of upper respiratory tract infections and other inflammatory and infectious diseases. … Andrographolide (HMPL-004) is a botanical product extracted from a herb that occurs naturally in China.

  3. Drug

    Ciluprevir

    go.drugbank.com/drugs/DB05868
    Investigational

    The compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.

  4. Target

    Maltoporin

    go.drugbank.com/bio_entities/BE0003212
    TargetTransporterEscherichia coli (strain K12)

    Also acts as a receptor for several bacteriophages including lambda (PubMed:4201774). Binds maltosaccharides; when LamB binds starch in soft agar, it inhibits motility (PubMed:2832377).

    Synonyms: Lambda receptor protein, Phage lambda receptor protein
  5. Drug

    Rolitetracycline

    go.drugbank.com/drugs/DB01301
    ApprovedWithdrawn

    A pyrrolidinylmethyl tetracycline.

  6. Drug

    Lenvatinib

    go.drugbank.com/drugs/DB09078
    ApprovedInvestigational

    These receptor tyrosine kinases (RTKs) located in the cell membrane play a central role in the activation of signal transduction pathways involved in the normal regulation of cellular processes, such as … Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4).

    Categories: Receptor Tyrosine Kinase Inhibitors
  7. Drug

    Bexotegrast

    go.drugbank.com/drugs/DB16515
    Investigational

    The compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in Series C financing to support further clinical … In addition, the compound is also currently in Phase 2a trials (NCT04565249) for the treatment of COVID-19 related acute respiratory distress syndrome[L31713].

  8. Drug

    Isocarboxazid

    go.drugbank.com/drugs/DB01247
    Approved

    It is a monoamine oxidase inhibitor.[A31930] It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders. … [T115] It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.

  9. Drug

    Sucralose

    go.drugbank.com/drugs/DB15049
    Investigational

    Sucralose is an artificial sweetener used as a sugar substitute.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Chromic nitrate

    go.drugbank.com/drugs/DB14527
    Approved