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Cretostimogene grenadenorepvec

It has been engineered to secrete GM-CSF, an immune stimulating hormone, which also serves as the adjuvant in cancer immunotherapy.

Receptor binding domain (RBD) SARS-CoV-2 (COVID-19) hepatitis B surface antigen (HBsAg) virus-like particle (VLP) vaccine

Regarding this vaccine specifically, it stimulates the immune system to produce anti-receptor binding domain antibodies[A226593].

PRX-07034

Glembatumumab vedotin

A conjugate of an anti-glycoprotein non-metastatic melanoma protein B mAb and monomethyl auristatin E for the treatment of melanoma and breast cancer.

SF1126

SF1126 is an integrin-targeted PI3 kinase inhibitor.

N4-Hydroxycytidine

[A193023] It has shown antiviral activity against Venezuelan equine encephalitis virus,[A193008] and the human coronavirus HCoV-NL63 _in vitro_. … [A193014] It is orally bioavailable in mice and distributes into tissue before becoming the active 5’-triphosphate form, which is incorporated into the genome of new virions, resulting in the accumulation

AVR-RD-02

It consists of autologous CD34+ enriched hematopoietic stem cells (HSCs) that have been genetically modified _ex vivo_ with a lentiviral vector (LV) to contain a ribonucleic acid (RNA) transcript that,

FT516

It is also a potential therapy for COVID-19.

Insulin-like growth factor II

It is believed to be a major fetal growth factor in contrast to insulin-like growth factor I, which is a major growth factor in adults.

Oglufanide

Oglufanide was originally developed to treat severe infectious disease in Russia (where it is a registered pharmaceutical), and was extensively studied in cancer clinical trials in the United States before