Oglufanide

DB05779InvestigationalSmall molecule

Oglufanide is a synthetic dipeptide immunomodulator in development for the treatment of chronic hepatitis C viral infection. Oglufanide was originally developed to treat severe infectious disease in Russia (where it... Oglufanide works as a regulator of the body's immune response, is being given by intranasal administration to patients with chronic hepatitis C viral infection.

Chemical structure of Oglufanide
Primary indication
Investigated for use/treatment in hepatitis (viral, C).Curator reviewed
Formula / weight
C16H19N3O5 · 333.344 g/mol (avg)
Also known as
alpha-Glutamyltryptophan · Glutamyltryptophan
Code names
IM 862

Resolves to

Compound
UNII4RHY598T5UCAS38101-59-6ChEMBLCHEMBL2111029ChEBI73512PubChem100094
Structure
InChIKeyLLEUXCDZPQOJMY-AAEUAGOBSA-NSMILESN[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O

What you can answer from here — as of September 16, 2026

39Drug interactionsStructured to mechanism, not free text
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4Clinical trialsPhase, status and sponsor resolved per trial
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Which companies are running trials of Oglufanide, in which indications and phases, and which of those programs are still active?

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