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Displaying results 4671 - 4680 of 9670 in total
  1. Drug

    Choline alfoscerate

    go.drugbank.com/drugs/DB04660
    Investigational

    (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem]

  2. Drug

    Hexobarbital

    go.drugbank.com/drugs/DB01355
    Experimental

    A barbiturate that is effective as a hypnotic and sedative.

  3. Drug

    OSI-7836

    go.drugbank.com/drugs/DB05837
    Experimental

    OSI Pharmaceuticals develops OSI-7836 as a next-generation gemcitabine. The anti-tumor activity of OSI-7836 appeares to be less schedule dependent than gemcitabine. … It is also more active than ara-C (another clinically used nucleoside analog) in all nine models and more active than either paclitaxel or cisplatin in the two lung xenograft models tested.

  4. Drug

    CERE-120

    go.drugbank.com/drugs/DB05637
    Investigational

    It was under investigation in clinical trials for the treatment of Parkinson's Disease. … CERE-120 is an investigational drug consisting of an adeno-associated virus (AAV) that was engineered to carry the human gene for neurturin, a neurotrophic (growth) factor.

  5. Drug

    Zamubafusp alfa

    go.drugbank.com/drugs/DB32269
    Investigational

    [L55038] It consists of a humanized IgG1 and p5R which is a pan-amyloid reactive peptide.[L55038]

  6. Drug

    Hycanthone

    go.drugbank.com/drugs/DB14061
    Experimental

    Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.

  7. Drug

    Ulimorelin

    go.drugbank.com/drugs/DB12128
    Investigational

    Ulimorelin is a novel small molecule ghrelin agonist being developed by Tranzyme Pharma as a first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility

  8. Drug

    Allovectin-7

    go.drugbank.com/drugs/DB17439
    Investigational

    It was discontinued after it failed to improve the objective response rate or overall survival versus first-line chemotherapy in malignant melanoma.[A255207]

  9. Drug

    NasoVAX

    go.drugbank.com/drugs/DB15859
    Investigational

    Created by Altimmune, Inc., NasoVAX is currently being developed for seasonal and pandemic use as it can activate humoral and cellular immune responses. … It is a vaccine administered through a nasal spray that expresses influenza hemagglutinin in nasal epithelial cells[L16313].

  10. Drug

    SR-9011

    go.drugbank.com/drugs/DB14014
    Experimental

    SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues