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INM005
go.drugbank.com/drugs/DB16499InvestigationalINM005 was under investigation in clinical trials for the treatment of COVID-19. It was studied for pharmacokinetics, efficacy, and safety in a completed trial (NCT04494984). … Additionally, a retrospective cohort study investigated the effectiveness and safety of specific hyperimmune equine serum for severe hospitalized COVID-19 patients (NCT04954235)
Synonyms: INM-005 (PURIFIED FAB'2 FRACTION OF EQUINE HYPERIMMUNE SERUM GENERATED FROM ANTIGENIC STIMULATION WITH THE SARS-COV2 RBD PROTEIN)Categories: Experimental Unapproved Treatments for COVID-19BMS-986142
go.drugbank.com/drugs/DB15291InvestigationalBMS-986142 is under investigation in clinical trial NCT02880670 (Pharmacokinetics and Metabolism Study of Radiolabeled BMS-986142 in Healthy Male Subjects).
Arbekacin
go.drugbank.com/drugs/DB06696InvestigationalAn semisynthetic aminoglycoside antibiotic. Often used for treatment of multi-resistant bacterial infection such as methicillin-resistant _Staphylococcus aureus_ (MRSA).
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseVibostolimab
go.drugbank.com/drugs/DB16420InvestigationalStage III Melanoma Who Are Candidates for Neoadjuvant Therapy (MK-3475-02C/KEYMAKER-U02)). … Vibostolimab is under investigation in clinical trial NCT04303169 (Substudy 02C: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With
Hydrocortisone butyrate
go.drugbank.com/drugs/DB14540ApprovedVet approvedSynonyms: 17-O-butyrylcortisolCategories: Corticosteroids, Moderately Potent (Group II)EDP1815
go.drugbank.com/drugs/DB16486InvestigationalEDP1815, was investigated in several clinical trials (NCT05066373, NCT05439941, NCT05682222, NCT03733353, NCT04603027, NCT04488575, NCT05121480, NCT04393246) to evaluate its safety and efficacy in conditions
Categories: Experimental Unapproved Treatments for COVID-19Chloropyramine
go.drugbank.com/drugs/DB08800InvestigationalIt is also indicated for Quincke's edema, allergic reactions to insect bites, food and drug allergies, and anaphylactic shock. … Chlorpyramine is a first generation antihistamine used in Eastern European countries to treat bronchial asthma as well as allergice rhinitis, allergic conjunctivitis, and other allergic reactions.
Categories: Antihistamines for Systemic Use, Antihistamines for Topical UseCTS-21166
go.drugbank.com/drugs/DB06073InvestigationalCTS-21166 is a small-molecule beta-secretase inhibitor, which is being developed as a disease-modifying treatment for Alzheimer's disease. … CTS-21166 is the only BACE1 inhibitor that has passed Phase I clinical trial thus far.
Noxytiolin
go.drugbank.com/drugs/DB13838ApprovedIt is used for THERAPEUTIC IRRIGATION of infected body cavities - bladder, peritoneum, etc. and as a spray for burns. … Local antibacterial that probably acts by releasing formaldehyde in aqueous solutions.
Carphenazine
go.drugbank.com/drugs/DB01038ApprovedWithdrawnCarphenazine is an antipsychotic drug, used in hospitalized patients in the management of chronic schizophrenic psychoses.