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Displaying results 461 - 470 of 10000 in total
  1. Drug

    Tilpisertib

    go.drugbank.com/drugs/DB18798
    Investigational

    Synonyms: 3-quinolinecarbonitrile, 6-(((s)-(1-bicyclo(1.1.1)pent-1-yl-1h-1,2,3-triazol-4-yl)(1,2-dihydro-2-methyl-1-oxo-5-isoquinolinyl)methyl)amino)-8-chloro-4-((2,2-dimethylpropyl)amino)-
  2. Drug

    Tretamine

    go.drugbank.com/drugs/DB14031
    Experimental

    Toxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,4,6-tris(1-aziridinyl)-s-triazine, 2,4,6-tri(1-aziridinyl)-1,3,5-triazine
  3. Drug

    Sakuranetin

    go.drugbank.com/drugs/DB08517
    Experimental

    Synonyms: (S)-(−)-4',5-dihydroxy-7-methoxyflavanone, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-chroman-4-oneCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  4. Drug

    Alrizomadlin

    go.drugbank.com/drugs/DB17549
    Investigational

    Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]

    Synonyms: 4-((3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo [2.2.2]octane-1-carboxylic acid, (3'r,4's,5'r)-4-((6-chloro-2-oxo-1,2-dihydro-spiro(indole-3,3'-pyrrolidin)e-4'-(3-chloro-2-fluoro -phenyl)-1'-ethyl-spiro(cyclohexane-1,2'-pyrrolidine)-5'-carbonyl)-amino)-bicyclo(2.2.2)octane-1-carboxylic
  5. Drug

    Bemcentinib

    go.drugbank.com/drugs/DB12411
    Investigational

    Bemcentinib has been investigated for the treatment of Non-Small Cell Lung Cancer.

    Synonyms: (S)-1-(6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N3-(7-(pyrrolidin-1-yl)- 6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)-1H-1,2,4-triazole-3,5-diamineCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Candicidin

    go.drugbank.com/drugs/DB01152
    ApprovedInvestigationalWithdrawn

    Candicidin is an antibiotic obtained from a streptomyces (Streptomyces griseus) and active against some fungi of the genus Candida (C. albicans). … Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynonyms: Levorin, Levorina
  7. Drug

    Iberdomide

    go.drugbank.com/drugs/DB12101
    Investigational

    drugs such as lenalidomide. … [L64055] Iberdomide has shown anti-tumor activity in multiple myeloma cells resistant to lenalidomide and pomalidomide, and as a CELMoD is designed to degrade Ikaros and Aiolos more potently than immunomodulatory

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: (S)-3-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 2,6-Piperidinedione, 3-(1,3-dihydro-4-((4-(4-morpholinylmethyl)phenyl)methoxy)-1-oxo-2H-isoindol-2-yl)-, (3S)-
  8. Drug

    WP-1066

    go.drugbank.com/drugs/DB12679
    Investigational

    WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central Nervous System Neoplasms.

    Synonyms: (E)-3-(6-Bromo-pyridin-2-yl)-2-cyano-N-((S)-1-phenyl-ethyl)-acryl amide, 2-PROPENAMIDE, 3-(6-BROMO-2-PYRIDINYL)-2-CYANO-N-((1S)-1-PHENYLETHYL)-, (2E)-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    Sutezolid

    go.drugbank.com/drugs/DB11905
    Investigational

    Sutezolid has been used in trials studying the treatment of Tuberculosis.

    Synonyms: ACETAMIDE, N-((3-(3-FLUORO-4-(4-THIOMORPHOLINYL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL)-, (S)-, N-{[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamideCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Dinoprostone

    go.drugbank.com/drugs/DB00917
    ApprovedInvestigational

    As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour. … Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts.

    Categories: Prostaglandins ESynonyms: (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid, (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid