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Levotofisopam
go.drugbank.com/drugs/DB19073InvestigationalLevotofisopam is under investigation in clinical trial NCT01519687 (Study of Levotofisopam 50 Mg Three Times a Day (TID) Administered for 7 Days on Hyperuricemia and Gout).
Synonyms: (s)-tofisopam, (-)-(5s)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepineCategories: Heterocyclic Compounds, 2-RingOxfendazole
go.drugbank.com/drugs/DB11446InvestigationalVet approvedOxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
Categories: Heterocyclic Compounds, 2-RingSynonyms: Fenbendazole S-oxide, 5-phenylsulfinyl-2-carbomethoxyaminobenzimidazoleTestosterone
go.drugbank.com/drugs/DB00624ApprovedInvestigationalTestosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.
Synonyms: 4-androsten-17β-ol-3-one, 17beta-hydroxy-4-androsten-3-oneInternational brands: Bio-T-Gel, Synandrol FTilpisertib
go.drugbank.com/drugs/DB18798InvestigationalSynonyms: 3-quinolinecarbonitrile, 6-(((s)-(1-bicyclo(1.1.1)pent-1-yl-1h-1,2,3-triazol-4-yl)(1,2-dihydro-2-methyl-1-oxo-5-isoquinolinyl)methyl)amino)-8-chloro-4-((2,2-dimethylpropyl)amino)-Alrizomadlin
go.drugbank.com/drugs/DB17549InvestigationalAlrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Synonyms: 4-((3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo [2.2.2]octane-1-carboxylic acid, (3'r,4's,5'r)-4-((6-chloro-2-oxo-1,2-dihydro-spiro(indole-3,3'-pyrrolidin)e-4'-(3-chloro-2-fluoro -phenyl)-1'-ethyl-spiro(cyclohexane-1,2'-pyrrolidine)-5'-carbonyl)-amino)-bicyclo(2.2.2)octane-1-carboxylicSakuranetin
go.drugbank.com/drugs/DB08517ExperimentalSynonyms: (S)-(−)-4',5-dihydroxy-7-methoxyflavanone, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-chroman-4-oneCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingTretamine
go.drugbank.com/drugs/DB14031ExperimentalToxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,4,6-tris(1-aziridinyl)-s-triazine, 2,4,6-tri(1-aziridinyl)-1,3,5-triazineBemcentinib
go.drugbank.com/drugs/DB12411InvestigationalBemcentinib has been investigated for the treatment of Non-Small Cell Lung Cancer.
Synonyms: (S)-1-(6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N3-(7-(pyrrolidin-1-yl)- 6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)-1H-1,2,4-triazole-3,5-diamineCategories: Heterocyclic Compounds, 1-RingIberdomide
go.drugbank.com/drugs/DB12101Investigationaldrugs such as lenalidomide. … [L64055] Iberdomide has shown anti-tumor activity in multiple myeloma cells resistant to lenalidomide and pomalidomide, and as a CELMoD is designed to degrade Ikaros and Aiolos more potently than immunomodulatory
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: (S)-3-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 2,6-Piperidinedione, 3-(1,3-dihydro-4-((4-(4-morpholinylmethyl)phenyl)methoxy)-1-oxo-2H-isoindol-2-yl)-, (3S)-WP-1066
go.drugbank.com/drugs/DB12679InvestigationalWP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central Nervous System Neoplasms.
Synonyms: (E)-3-(6-Bromo-pyridin-2-yl)-2-cyano-N-((S)-1-phenyl-ethyl)-acryl amide, 2-PROPENAMIDE, 3-(6-BROMO-2-PYRIDINYL)-2-CYANO-N-((1S)-1-PHENYLETHYL)-, (2E)-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring