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Displaying results 461 - 470 of 10000 in total
  1. Drug

    Hydroxyamphetamine

    go.drugbank.com/drugs/DB09352
    Approved

    Hydroxyamphetamine is a derivative of amphetamines. Hydroxyamphetamine is intended mainly as local eye drops for diagnostic purposes.

    Synonyms: 4-(2-aminopropyl)phenol, 4-hydroxyamphetamine
  2. Drug

    Tetrabenazine

    go.drugbank.com/drugs/DB04844
    Approved

    A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders. … It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August 15, 2008.

    Synonyms: 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one, 2-oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizineCategories: Heterocyclic Compounds, 2-Ring, Vesicular Monoamine Transporter 2 Inhibitor
  3. Drug

    Tolnaftate

    go.drugbank.com/drugs/DB00525
    ApprovedVet approved

    Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm.

    Synonyms: O-2-Naphthyl m,N-dimethylthiocarbanilate, m,N-Dimethylthiocarbanilic acid O-2-naphthyl esterInternational brands: NP-27
  4. Drug

    Amisometradine

    go.drugbank.com/drugs/DB19368
    ApprovedWithdrawn

    Synonyms: 2,4(1h,3h)-pyrimidinedione, 6-amino-3-methyl-1-(2-methyl-2-propenyl)-, 6-amino-3-methyl-1-(2-methylallyl)-2,4(1h,3h)-pyrimidinedione
  5. Drug

    Foslevodopa

    go.drugbank.com/drugs/DB16683
    Approved

    Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants

    Mixtures: Produodopa 240 mg/ml + 12 mg/ml InfusionslösungSynonyms: 3-hydroxy-O-phosphono-L-tyrosine, Levodopa-4'-monophosphate
  6. Drug

    Ergotamine

    go.drugbank.com/drugs/DB00696
    Approved

    A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.

    Synonyms: (5'α)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trioneMixtures: CAFERGOT 1 MG/100 MG TABLET, 30 ADET, ERGOTAMINA/CAFEINA 1/100 MG
  7. Drug

    (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one

    go.drugbank.com/drugs/DB08236
    Experimental

    Synonyms: (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
  8. Drug

    3-Chloro-4-Hydroxyphenylglycine

    go.drugbank.com/drugs/DB03898
    Experimental

    Synonyms: 3-Chloro-4-Hydroxyphenylglycine
  9. Drug

    Buprenorphine

    go.drugbank.com/drugs/DB00921
    ApprovedIllicitInvestigationalVet approved

    Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain. … [A186263,A186266,A186269] Buprenorphine acts as a partial mu-opioid receptor agonist with a high affinity for the receptor, but lower intrinsic activity compared to other full mu-opioid agonists such

    Mixtures: Bupensan Duo 4 mg/1 mg-Sublingualtabletten, SUBOXONE 8 MG/2 MG DILALTI TABLET, 7 ADETCategories: Heterocyclic Compounds with 4 or More Rings, P-glycoprotein inhibitors
  10. Drug

    Vonoprazan

    go.drugbank.com/drugs/DB11739
    ApprovedInvestigational

    Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H<sup>+</sup>, K<sup>+</sup>-ATPase-mediated gastric acid secretion. … [A253702] In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin and clarithromycin for the treatment of _H. pylori_ infection.

    Synonyms: 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamineCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates