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Golodirsen
go.drugbank.com/drugs/DB15593ApprovedInvestigationalGolodirsen is a morpholino antisense oligomer designed to treat about 8% of patients with Duchenne Muscular Dystrophy (DMD). … [A188580,T756] A similar drug used in the treatment of other types of DMD is [eteplirsen], which targets a different genetic mutation.
Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingBrilliant blue G
go.drugbank.com/drugs/DB15594ApprovedBrilliant blue G, like its name, imparts a vibrant blue color, facilitating identification of the ILM. It was approved by the FDA for ophthalmic use on December 20, 2019.[L10830] … Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Brilliant blue G, Coomassie Brilliant Blue GEbola Zaire vaccine (live, attenuated)
go.drugbank.com/drugs/DB15595ApprovedInvestigational[L10866] In 2014, Merck Inc. signed a licensing agreement with NewLink for further development and marketing. … [L10854] Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease.
Synonyms: Ebola Zaire Vaccine (rVSV∆G-ZEBOV-GP, live), EBOLA ZAÏRE VACCINE (rVSV [DELTA] G-ZEBOV-GP, LIVE)NNZ-2591
go.drugbank.com/drugs/DB15601InvestigationalNNZ-2591 (cyclo-L-glycyl-L-2-allylproline)[A189390] is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been … It was granted Orphan Drug Designation by the FDA in October 2019[L11103] and was granted a patent by the European Patent Office in December 2019.
Categories: Heterocyclic Compounds, 1-RingSynonyms: Cyclo(-L-glycyl-L-2-allylproline), Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-8a-(2-propenyl)-, (8aR)-JPC-3210
go.drugbank.com/drugs/DB15609ExperimentalJPC-3210 is a potent antimalarial agent. … antimalarial activity against multidrug-resistant _Plasmodium falciparum_ lines, low cytotoxicity, potent in vivo efficacy against murine malaria, and favourable preclinical pharmacokinetics including a
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 CYP3A InhibitorsPrevitamin D(3)
go.drugbank.com/drugs/DB15614InvestigationalCategories: Vitamin D and AnaloguesSynonyms: Previtamin D(3), Previtamin DREC-994
go.drugbank.com/drugs/DB15616InvestigationalREC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous malformation (CCM).
Ferric derisomaltose
go.drugbank.com/drugs/DB15617ApprovedInvestigational[A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. This drug is a complex of iron (III) hydroxide and derisomaltose.
Products: MONOFER® SOLUTION FOR INJECTION OR INFUSION 100 MG/MLSpesolimab
go.drugbank.com/drugs/DB15626ApprovedInvestigationalIt is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Products: Spevigo 450 mg/7,5 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 2 ADETPabinafusp alfa
go.drugbank.com/drugs/DB15633InvestigationalPabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Synonyms: -2-SULFATASE, DISULFIDE WITH HUMAN-MUS MUSCULUS MONO, Immunoglobulin G1-kappa, anti-(human transferrin receptor 1, tfr1) humanized monoclonal antibody, fused with human iduronate-2-sulfatase, glycoform alfa: